Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins

Mitotic spindle microtubules (MTs) undergo continuous poleward flux, whose driving force and function in humans remain unclear. Here, we combined loss‐of‐function screenings with analysis of MT‐dynamics in human cells to investigate the molecular mechanisms underlying MT‐flux. We report that kinesin...

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Veröffentlicht in:The EMBO journal 2020-12, Vol.39 (23), p.e105432-n/a
Hauptverfasser: Steblyanko, Yulia, Rajendraprasad, Girish, Osswald, Mariana, Eibes, Susana, Jacome, Ariana, Geley, Stephan, Pereira, António J, Maiato, Helder, Barisic, Marin
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Sprache:eng
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