Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes

Background/aimsBest-corrected visual acuity (BCVA) is the most common primary endpoint in treatment trials for choroideremia (CHM) but the long-term natural history of BCVA is unclear.MethodsWe searched in seven databases to identify studies that reported BCVA of untreated eyes with CHM. We sought i...

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Veröffentlicht in:	British journal of ophthalmology 2021-02, Vol.105 (2), p.271-278
Hauptverfasser:	Shen, Liangbo L, Ahluwalia, Aneesha, Sun, Mengyuan, Young, Benjamin K, Grossetta Nardini, Holly K, Del Priore, Lucian V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Bias Choroideremia - physiopathology Databases, Factual Diabetic retinopathy Female Fluorescein Angiography Follow-Up Studies Humans Male Medical prognosis Meta-analysis Middle Aged Natural history Ophthalmology Patients Regression analysis Sensitivity analysis Statistical analysis Survival analysis Systematic review Tomography, Optical Coherence Visual acuity Visual Acuity - physiology
Online-Zugang:	Volltext
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