Convalescent plasma therapy for B-cell–depleted patients with protracted COVID-19

Anti-CD20 monoclonal antibodies are widely used for the treatment of hematological malignancies or autoimmune disease but may be responsible for a secondary humoral deficiency. In the context of COVID-19 infection, this may prevent the elicitation of a specific SARS-CoV-2 antibody response. We repor...

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Veröffentlicht in:	Blood 2020-11, Vol.136 (20), p.2290-2295
Hauptverfasser:	Hueso, Thomas, Pouderoux, Cécile, Péré, Hélène, Beaumont, Anne-Lise, Raillon, Laure-Anne, Ader, Florence, Chatenoud, Lucienne, Eshagh, Déborah, Szwebel, Tali-Anne, Martinot, Martin, Camou, Fabrice, Crickx, Etienne, Michel, Marc, Mahevas, Matthieu, Boutboul, David, Azoulay, Elie, Joseph, Adrien, Hermine, Olivier, Rouzaud, Claire, Faguer, Stanislas, Petua, Philippe, Pommeret, Fanny, Clerc, Sébastien, Planquette, Benjamin, Merabet, Fatiha, London, Jonathan, Zeller, Valérie, Ghez, David, Veyer, David, Ouedrani, Amani, Gallian, Pierre, Pacanowski, Jérôme, Mékinian, Arsène, Garnier, Marc, Pirenne, France, Tiberghien, Pierre, Lacombe, Karine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies, Viral - immunology B-Lymphocytes - immunology B-Lymphocytes - pathology Betacoronavirus - immunology Blood Component Transfusion Brief Report Coronavirus Infections - blood Coronavirus Infections - immunology Coronavirus Infections - therapy Coronavirus Infections - virology COVID-19 Female France Hematologic Neoplasms - complications Humans Immune Sera - administration & dosage Immunization, Passive Lymphopenia - etiology Lymphopenia - pathology Lymphopenia - therapy Male Middle Aged Pandemics Pneumonia, Viral - blood Pneumonia, Viral - immunology Pneumonia, Viral - therapy Pneumonia, Viral - virology SARS-CoV-2
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