Recalling the COVID-19 lockdown: Insights from patients with epilepsy
•COVID-19 lockdowns are linked to health worsening in patients with epilepsy.•Proper AED use may be especially important to prevent seizure exacerbation.•The access to epilepsy services and their quality is suboptimal during lockdown. The purpose of our study was to explore health changes among peop...
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| Veröffentlicht in: | Epilepsy & behavior 2021-02, Vol.115, p.107573-107573, Article 107573 |
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| creator | Puteikis, Kristijonas Jasionis, Arminas Mameniškienė, Rūta |
| description | •COVID-19 lockdowns are linked to health worsening in patients with epilepsy.•Proper AED use may be especially important to prevent seizure exacerbation.•The access to epilepsy services and their quality is suboptimal during lockdown.
The purpose of our study was to explore health changes among people with epilepsy (PWE) during a national COVID-19 lockdown in the context of patients’ clinical characteristics and their experience of receiving epilepsy-related medical services.
A questionnaire was distributed for adult PWE both online and at a tertiary epilepsy center after the end of a national lockdown in Lithuania. PWE were asked to evaluate their health status during the lockdown and estimate changes in their seizure patterns. Additional questions concerned the accessibility and quality of epilepsy-related consultations.
The study sample consisted of 143 PWE (59 [41.3%] male, mean age 35.1 ± 13.4 years), 94 (65.7%) completed the survey in person, 49 (34.3%) – online. A deterioration in reported physical and mental health during lockdown was observed (Z = −4.604, p |
| doi_str_mv | 10.1016/j.yebeh.2020.107573 |
| format | Article |
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The purpose of our study was to explore health changes among people with epilepsy (PWE) during a national COVID-19 lockdown in the context of patients’ clinical characteristics and their experience of receiving epilepsy-related medical services.
A questionnaire was distributed for adult PWE both online and at a tertiary epilepsy center after the end of a national lockdown in Lithuania. PWE were asked to evaluate their health status during the lockdown and estimate changes in their seizure patterns. Additional questions concerned the accessibility and quality of epilepsy-related consultations.
The study sample consisted of 143 PWE (59 [41.3%] male, mean age 35.1 ± 13.4 years), 94 (65.7%) completed the survey in person, 49 (34.3%) – online. A deterioration in reported physical and mental health during lockdown was observed (Z = −4.604, p < 0.0001 and Z = −4.253, p < 0.0001, respectively) and 22 (15.4%) PWE reported seizure exacerbation. In an ordinal logistic regression model (analysis of data from all participants), baseline seizure frequency (b = 0.413, p = 0.031), reported physical health before lockdown (b = −0.462, p = 0.031) and the ease of proper antiepileptic drug (AED) use during the imposed restrictions (b = −0.535, p = 0.006) were statistically significant variables associated with changes in seizure frequency. The latter were not affected by modifications in AED use (Mann–Whitney U = 1127.0, p = 0.307) irrespective of the data collection method.
With teleconsultations being predominant during the lockdown, an overall decline in the quality of epilepsy-related consultations was observed (Z = −2.895, p = 0.004). Among all participants, 46 (32.2%) lost an epilepsy-related consultation or medical service because of the lockdown. This loss was found to be associated with seizure exacerbation (Mann–Whitney U = 1622.5, p = 0.046).
Our study indicates that a national COVID-19 lockdown may have led to worse seizure control and health status in some PWE. Easy access to AEDs and their appropriate use may be especially useful to prevent seizure exacerbation during strict COVID-19 restrictions. The quality and accessibility of remote epilepsy-related consultations was suboptimal and may require further improvement during disruption of in-person services.</description><identifier>ISSN: 1525-5050</identifier><identifier>EISSN: 1525-5069</identifier><identifier>DOI: 10.1016/j.yebeh.2020.107573</identifier><identifier>PMID: 33268021</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Anticonvulsants - therapeutic use ; Communicable Disease Control - methods ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - prevention & control ; COVID-19 - psychology ; Epilepsy ; Epilepsy - drug therapy ; Epilepsy - epidemiology ; Epilepsy - psychology ; Female ; Humans ; Lithuania - epidemiology ; Lockdown ; Male ; Mental Recall - physiology ; Middle Aged ; Remote Consultation - methods ; Retrospective Studies ; Seizure exacerbation ; Surveys and Questionnaires ; Telemedicine ; Young Adult</subject><ispartof>Epilepsy & behavior, 2021-02, Vol.115, p.107573-107573, Article 107573</ispartof><rights>2020</rights><rights>Copyright © 2020. Published by Elsevier Inc.</rights><rights>2020 Published by Elsevier Inc. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-9819fb2446a24f2b63ad6f4c63c3d9e4b9d05a639dfc99ddc1997bf770da6a213</citedby><cites>FETCH-LOGICAL-c459t-9819fb2446a24f2b63ad6f4c63c3d9e4b9d05a639dfc99ddc1997bf770da6a213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.yebeh.2020.107573$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,777,781,882,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33268021$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Puteikis, Kristijonas</creatorcontrib><creatorcontrib>Jasionis, Arminas</creatorcontrib><creatorcontrib>Mameniškienė, Rūta</creatorcontrib><title>Recalling the COVID-19 lockdown: Insights from patients with epilepsy</title><title>Epilepsy & behavior</title><addtitle>Epilepsy Behav</addtitle><description>•COVID-19 lockdowns are linked to health worsening in patients with epilepsy.•Proper AED use may be especially important to prevent seizure exacerbation.•The access to epilepsy services and their quality is suboptimal during lockdown.
The purpose of our study was to explore health changes among people with epilepsy (PWE) during a national COVID-19 lockdown in the context of patients’ clinical characteristics and their experience of receiving epilepsy-related medical services.
A questionnaire was distributed for adult PWE both online and at a tertiary epilepsy center after the end of a national lockdown in Lithuania. PWE were asked to evaluate their health status during the lockdown and estimate changes in their seizure patterns. Additional questions concerned the accessibility and quality of epilepsy-related consultations.
The study sample consisted of 143 PWE (59 [41.3%] male, mean age 35.1 ± 13.4 years), 94 (65.7%) completed the survey in person, 49 (34.3%) – online. A deterioration in reported physical and mental health during lockdown was observed (Z = −4.604, p < 0.0001 and Z = −4.253, p < 0.0001, respectively) and 22 (15.4%) PWE reported seizure exacerbation. In an ordinal logistic regression model (analysis of data from all participants), baseline seizure frequency (b = 0.413, p = 0.031), reported physical health before lockdown (b = −0.462, p = 0.031) and the ease of proper antiepileptic drug (AED) use during the imposed restrictions (b = −0.535, p = 0.006) were statistically significant variables associated with changes in seizure frequency. The latter were not affected by modifications in AED use (Mann–Whitney U = 1127.0, p = 0.307) irrespective of the data collection method.
With teleconsultations being predominant during the lockdown, an overall decline in the quality of epilepsy-related consultations was observed (Z = −2.895, p = 0.004). Among all participants, 46 (32.2%) lost an epilepsy-related consultation or medical service because of the lockdown. This loss was found to be associated with seizure exacerbation (Mann–Whitney U = 1622.5, p = 0.046).
Our study indicates that a national COVID-19 lockdown may have led to worse seizure control and health status in some PWE. Easy access to AEDs and their appropriate use may be especially useful to prevent seizure exacerbation during strict COVID-19 restrictions. The quality and accessibility of remote epilepsy-related consultations was suboptimal and may require further improvement during disruption of in-person services.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Communicable Disease Control - methods</subject><subject>COVID-19</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - prevention & control</subject><subject>COVID-19 - psychology</subject><subject>Epilepsy</subject><subject>Epilepsy - drug therapy</subject><subject>Epilepsy - epidemiology</subject><subject>Epilepsy - psychology</subject><subject>Female</subject><subject>Humans</subject><subject>Lithuania - epidemiology</subject><subject>Lockdown</subject><subject>Male</subject><subject>Mental Recall - physiology</subject><subject>Middle Aged</subject><subject>Remote Consultation - methods</subject><subject>Retrospective Studies</subject><subject>Seizure exacerbation</subject><subject>Surveys and Questionnaires</subject><subject>Telemedicine</subject><subject>Young Adult</subject><issn>1525-5050</issn><issn>1525-5069</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UdtqGzEQFaEht-YLAmUf-7KOLivJKrQQ3FwMgUBp-yq00qxX7nq1ldYJ_vvKdWKSlzyNZnTOmeEchC4InhBMxOVysoEa2gnFdDuRXLIDdEI45SXHQn3Yvzk-RqcpLTEmhDNyhI4Zo2KKKTlB1z_Amq7z_aIYWyhmD7_n30uiii7YPy489V-KeZ_8oh1T0cSwKgYzeuhz9-THtoDBdzCkzUd02JguwflzPUO_bq5_zu7K-4fb-ezqvrQVV2OppkQ1Na0qYWjV0Fow40RTWcEscwqqWjnMjWDKNVYp5yxRStaNlNiZTCHsDH3b6Q7regXO5kui6fQQ_crEjQ7G67c_vW_1IjzqLIEllVng87NADH_XkEa98slC15kewjppWgkhxVRInqFsB7UxpBSh2a8hWG8D0Ev9PwC9DUDvAsisT68v3HNeHM-ArzsAZJ8ePUSdbHbUgvMR7Khd8O8u-Aeh1JhM</recordid><startdate>20210201</startdate><enddate>20210201</enddate><creator>Puteikis, Kristijonas</creator><creator>Jasionis, Arminas</creator><creator>Mameniškienė, Rūta</creator><general>Elsevier Inc</general><general>Published by Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210201</creationdate><title>Recalling the COVID-19 lockdown: Insights from patients with epilepsy</title><author>Puteikis, Kristijonas ; Jasionis, Arminas ; Mameniškienė, Rūta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-9819fb2446a24f2b63ad6f4c63c3d9e4b9d05a639dfc99ddc1997bf770da6a213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Communicable Disease Control - methods</topic><topic>COVID-19</topic><topic>COVID-19 - epidemiology</topic><topic>COVID-19 - prevention & control</topic><topic>COVID-19 - psychology</topic><topic>Epilepsy</topic><topic>Epilepsy - drug therapy</topic><topic>Epilepsy - epidemiology</topic><topic>Epilepsy - psychology</topic><topic>Female</topic><topic>Humans</topic><topic>Lithuania - epidemiology</topic><topic>Lockdown</topic><topic>Male</topic><topic>Mental Recall - physiology</topic><topic>Middle Aged</topic><topic>Remote Consultation - methods</topic><topic>Retrospective Studies</topic><topic>Seizure exacerbation</topic><topic>Surveys and Questionnaires</topic><topic>Telemedicine</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Puteikis, Kristijonas</creatorcontrib><creatorcontrib>Jasionis, Arminas</creatorcontrib><creatorcontrib>Mameniškienė, Rūta</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Epilepsy & behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Puteikis, Kristijonas</au><au>Jasionis, Arminas</au><au>Mameniškienė, Rūta</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recalling the COVID-19 lockdown: Insights from patients with epilepsy</atitle><jtitle>Epilepsy & behavior</jtitle><addtitle>Epilepsy Behav</addtitle><date>2021-02-01</date><risdate>2021</risdate><volume>115</volume><spage>107573</spage><epage>107573</epage><pages>107573-107573</pages><artnum>107573</artnum><issn>1525-5050</issn><eissn>1525-5069</eissn><abstract>•COVID-19 lockdowns are linked to health worsening in patients with epilepsy.•Proper AED use may be especially important to prevent seizure exacerbation.•The access to epilepsy services and their quality is suboptimal during lockdown.
The purpose of our study was to explore health changes among people with epilepsy (PWE) during a national COVID-19 lockdown in the context of patients’ clinical characteristics and their experience of receiving epilepsy-related medical services.
A questionnaire was distributed for adult PWE both online and at a tertiary epilepsy center after the end of a national lockdown in Lithuania. PWE were asked to evaluate their health status during the lockdown and estimate changes in their seizure patterns. Additional questions concerned the accessibility and quality of epilepsy-related consultations.
The study sample consisted of 143 PWE (59 [41.3%] male, mean age 35.1 ± 13.4 years), 94 (65.7%) completed the survey in person, 49 (34.3%) – online. A deterioration in reported physical and mental health during lockdown was observed (Z = −4.604, p < 0.0001 and Z = −4.253, p < 0.0001, respectively) and 22 (15.4%) PWE reported seizure exacerbation. In an ordinal logistic regression model (analysis of data from all participants), baseline seizure frequency (b = 0.413, p = 0.031), reported physical health before lockdown (b = −0.462, p = 0.031) and the ease of proper antiepileptic drug (AED) use during the imposed restrictions (b = −0.535, p = 0.006) were statistically significant variables associated with changes in seizure frequency. The latter were not affected by modifications in AED use (Mann–Whitney U = 1127.0, p = 0.307) irrespective of the data collection method.
With teleconsultations being predominant during the lockdown, an overall decline in the quality of epilepsy-related consultations was observed (Z = −2.895, p = 0.004). Among all participants, 46 (32.2%) lost an epilepsy-related consultation or medical service because of the lockdown. This loss was found to be associated with seizure exacerbation (Mann–Whitney U = 1622.5, p = 0.046).
Our study indicates that a national COVID-19 lockdown may have led to worse seizure control and health status in some PWE. Easy access to AEDs and their appropriate use may be especially useful to prevent seizure exacerbation during strict COVID-19 restrictions. The quality and accessibility of remote epilepsy-related consultations was suboptimal and may require further improvement during disruption of in-person services.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>33268021</pmid><doi>10.1016/j.yebeh.2020.107573</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Anticonvulsants - therapeutic use Communicable Disease Control - methods COVID-19 COVID-19 - epidemiology COVID-19 - prevention & control COVID-19 - psychology Epilepsy Epilepsy - drug therapy Epilepsy - epidemiology Epilepsy - psychology Female Humans Lithuania - epidemiology Lockdown Male Mental Recall - physiology Middle Aged Remote Consultation - methods Retrospective Studies Seizure exacerbation Surveys and Questionnaires Telemedicine Young Adult |
| title | Recalling the COVID-19 lockdown: Insights from patients with epilepsy |
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