Deformable Liposomal Hydrogel for Dermal and Transdermal Delivery of Meloxicam

Meloxicam (MX) is a potent hydrophobic non-steroidal anti-inflammatory drug used to reduce inflammation and pain. However, its oral dosage form can cause many adverse gastrointestinal effects. In the present study, a poloxamer P407 based hydrogel system containing transfersomes or flavosomes has bee...

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Veröffentlicht in:	International journal of nanomedicine 2020-01, Vol.15, p.9319-9335
Hauptverfasser:	Zhang, Zhang Julia, Osmałek, Tomasz, Michniak-Kohn, Bozena
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Administration, Topical Alzheimer's disease Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - metabolism Arthritis Bioflavonoids Chromatography Drug dosages Flavones Flavonoids Health aspects High performance liquid chromatography Humans Hydrogels Hydrogels - chemistry Hydrophobic and Hydrophilic Interactions Instrument industry Lipids Liposomes - chemistry Male Mechanical Phenomena Meloxicam Meloxicam - administration & dosage Meloxicam - metabolism Original Research Particle Size Permeability Skin Skin - metabolism Skin Absorption Swine Viscosity
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