Antarctic Krill Oil Ameliorates Monosodium Iodoacetate-Induced Irregularities in Articular Cartilage and Inflammatory Response in the Rat Models of Osteoarthritis

The aim of this study was to examine the effects of Antarctic krill oil (FJH-KO) in a rat model of monosodium iodoacetate (MIA) induced osteoarthritis. The effect of FJH-KO on the development and severity of MIA-induced osteoarthritis was assessed using hematoxylin and eosin (H&E) staining and m...

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Veröffentlicht in:	Nutrients 2020-11, Vol.12 (11), p.3550, Article 3550
Hauptverfasser:	Lee, Minhee, Kim, Dakyung, Park, Soo-Jeung, Yun, Jeong Moon, Oh, Dong Hwan, Lee, Jeongmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Antarctic krill oil Antarctic Regions Arthritis Biomedical materials Bone density Cartilage Cartilage (articular) Cartilage diseases Cartilage, Articular - drug effects Cartilage, Articular - pathology Chemical compounds Collagen Computed tomography Cytokines Cytokines - blood Degeneration Diet Dietary supplements Disease Models, Animal Euphausiacea - chemistry Functional foods & nutraceuticals Gene expression IL-1β Inflammation Inflammatory response Interleukin 6 Iodoacetates - adverse effects Iodoacetic Acid - adverse effects Irregularities Krill Life Sciences & Biomedicine Male monoiodoacetate Nutrition & Dietetics Oils - pharmacology Osteoarthritis Osteoarthritis - drug therapy Osteoarthritis - pathology Pain Pharmacology Polar environments Prostaglandin E2 Rats Rats, Sprague-Dawley RNA, Messenger - metabolism Rodents Science & Technology Statistical analysis Tumor necrosis factor-α X-Ray Microtomography
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