Prognostic Significance of COVID-19 Receptor ACE2 and Recommendation for Antihypertensive Drug in Renal Cell Carcinoma

Purpose. Owing to its worldwide spread, the coronavirus disease (COVID-19) epidemic was declared a pandemic by the World Health Organization on March 11, 2020. Angiotensin-converting enzyme 2 (ACE2) is the outer surface protein of the cell membrane that is abundantly distributed in the heart, lungs,...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-7
Hauptverfasser:	Kim, Yun Hak, Ko, Dai Sik, Ko, Yeji, Kim, Kihun
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE inhibitors ACE2 Adenocarcinoma Angiotensin Angiotensin-converting enzyme 2 Angiotensin-Converting Enzyme 2 - biosynthesis Antihypertensive Agents - administration & dosage Antihypertensive drugs Antihypertensives Blood pressure Cancer Carcinoma, Renal cell Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - mortality Cell membranes Clear cell-type renal cell carcinoma Confidence intervals Coronaviridae Coronaviruses COVID-19 COVID-19 - metabolism COVID-19 - mortality COVID-19 Drug Treatment Disease-Free Survival Dosage and administration Drug therapy Epidemics Female Gene expression Gene Expression Regulation, Neoplastic - drug effects Genomes Glioblastoma Humans Hypertension Kidney cancer Kidney Neoplasms - drug therapy Kidney Neoplasms - metabolism Kidney Neoplasms - mortality Life span Male Melanoma Membrane proteins Molecular docking Neoplasm Proteins - biosynthesis Pandemics Patient outcomes Patients Peptidyl-dipeptidase A Prognosis Prostate Prostate cancer Rank tests Regression analysis Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Statistical analysis Statistics Survival Survival analysis Survival Rate Thyroid Thyroid cancer Thyroid carcinoma Viral diseases Viral infections Viruses
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