Analysis of polymorphisms of canine Cytochrome P 450‐CYP2D15

Cytochrome P450 (CYP) proteins constitute a large ancient family of oxidative enzymes essential for the efficient elimination of a wide variety of clinically used drugs. Polymorphic variants of human CYP2D6 are associated with the conversion rate and efficacy of several drugs such as antidepressants...

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Veröffentlicht in:	Journal of veterinary pharmacology and therapeutics 2020-11, Vol.43 (6), p.602-607
Hauptverfasser:	Hagen, Marjan A. E., Schipper, Louska, Oosterveer‐van der Doelen, Marjolein A. M., Vos‐Loohuis, Manon, Gehring, Ronette, Leegwater, Peter A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Aryl Hydrocarbon Hydroxylases - genetics Base Sequence canine CYP2D6 cytochrome P 450‐CYP2D15 dog Dogs - genetics Gene Expression Regulation, Enzymologic - genetics genetic polymorphisms Original pharmacogenetics Polymorphism, Genetic
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