Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease

Abstract Clinical observations have linked tobacco smoking with increased type 2 diabetes risk. Mendelian randomization analysis has recently suggested smoking may be a causal risk factor for type 2 diabetes. However, this association could be mediated by additional risk factors correlated with smok...

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Veröffentlicht in:	Human molecular genetics 2020-11, Vol.29 (19), p.3327-3337
Hauptverfasser:	Thom, Christopher S, Ding, Zhuoran, Levin, Michael G, Damrauer, Scott M, Lee, Kyung Min, Lynch, Julie, Chang, Kyong-Mi, Tsao, Philip S, Cho, Kelly, Wilson, Peter W F, Assimes, Themistocles L, Sun, Yan V, O’Donnell, Christopher J, Vujkovic, Marijana, Voight, Benjamin F
Format:	Artikel
Sprache:	eng
Schlagworte:	Association Studies
Online-Zugang:	Volltext
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