Pharmacokinetic and Pharmacodynamic Factors Contribute to Synergism between Let-7c-5p and 5-Fluorouracil in Inhibiting Hepatocellular Carcinoma Cell Viability

Pharmacological interventions for hepatocellular carcinoma (HCC) are hindered by complex factors, and rational combination therapy may be developed to improve therapeutic outcomes. Very recently, we have identified a bioengineered microRNA let-7c-5p (or let-7c) agent as an effective inhibitor agains...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Drug metabolism and disposition 2020-12, Vol.48 (12), p.1257-1263
Hauptverfasser:	Jilek, Joseph L., Tu, Mei-Juan, Zhang, Chao, Yu, Ai-Ming
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!