Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study

Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Medicine (Baltimore) 2020-11, Vol.99 (47), p.e23407-e23407
Hauptverfasser: Liu, Han, Gao, Jinying, Wang, Yangyang, Jie, Jing, Luo, Jingjing, Xu, You, Sun, Hongying, Song, Lei, Li, Dan, Peng, Liping, Hua, Shucheng
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page e23407
container_issue 47
container_start_page e23407
container_title Medicine (Baltimore)
container_volume 99
creator Liu, Han
Gao, Jinying
Wang, Yangyang
Jie, Jing
Luo, Jingjing
Xu, You
Sun, Hongying
Song, Lei
Li, Dan
Peng, Liping
Hua, Shucheng
description Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.
doi_str_mv 10.1097/MD.0000000000023407
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7676609</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2463105631</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3551-a861403ba3c59b58a1182e622f87ea7f4349174655b61656415236abc05739dd3</originalsourceid><addsrcrecordid>eNpdkV1vFCEUhonR2LX6C0wMl23SqXwzeGHS7FZt06Y36i1hGKaDsrDCzDa98beL3bZ-cAE5nPc8kDwAvMboGCMl316ujtGfRShD8glYYE5Fw5VgT8Gi3vJGKsn2wItSviGEqSTsOdijlGDZtmIBfp5ufO_WPoV07a0J0MQe2uDjXWFHk42dXPZl8rbANECCsIIxbV3tppyi2fo8F9j74kxx8GB59fVs1WB1CH2E576SjuBy9NG8gyewd8Vmv5n81sEyzf3tS_BsMKG4V_fnPvjy4fTz8lNzcfXxbHly0VjKOW5MKzBDtDPUctXx1mDcEicIGVrpjBwYZQpLJjjvBBZcMMwJFaaziEuq-p7ug_c77mbu1q63Lk7ZBL3Jfm3yrU7G63870Y_6Om21FFIIpCrg4B6Q04_ZlUmvfbEuBBNdmosmTFCMeN1qlO6iNqdSshsen8FI_zanL1f6f3N16s3fP3yceVBVA2wXuEmhGinfw3zjsh6dCdN4x-NSkYagaggThJqquwr_Bcltols</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2463105631</pqid></control><display><type>article</type><title>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Wolters Kluwer Open Health</source><source>IngentaConnect Free/Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Liu, Han ; Gao, Jinying ; Wang, Yangyang ; Jie, Jing ; Luo, Jingjing ; Xu, You ; Sun, Hongying ; Song, Lei ; Li, Dan ; Peng, Liping ; Hua, Shucheng</creator><creatorcontrib>Liu, Han ; Gao, Jinying ; Wang, Yangyang ; Jie, Jing ; Luo, Jingjing ; Xu, You ; Sun, Hongying ; Song, Lei ; Li, Dan ; Peng, Liping ; Hua, Shucheng</creatorcontrib><description>Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000023407</identifier><identifier>PMID: 33217886</identifier><language>eng</language><publisher>United States: Lippincott Williams &amp; Wilkins</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; Child ; China - epidemiology ; Coronavirus Infections - complications ; Coronavirus Infections - epidemiology ; Coronavirus Infections - virology ; Cough - epidemiology ; Cough - virology ; COVID-19 ; Fatigue - epidemiology ; Fatigue - virology ; Female ; Fever - epidemiology ; Fever - virology ; Hospitalization - statistics &amp; numerical data ; Humans ; Lung - diagnostic imaging ; Lung - virology ; Lymphopenia - epidemiology ; Lymphopenia - virology ; Male ; Middle Aged ; Observational Study ; Pandemics ; Pneumonia, Viral - complications ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - virology ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index ; Tomography, X-Ray Computed - statistics &amp; numerical data ; Young Adult</subject><ispartof>Medicine (Baltimore), 2020-11, Vol.99 (47), p.e23407-e23407</ispartof><rights>Lippincott Williams &amp; Wilkins</rights><rights>Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3551-a861403ba3c59b58a1182e622f87ea7f4349174655b61656415236abc05739dd3</cites><orcidid>0000-0002-4531-1537</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676609/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676609/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33217886$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Han</creatorcontrib><creatorcontrib>Gao, Jinying</creatorcontrib><creatorcontrib>Wang, Yangyang</creatorcontrib><creatorcontrib>Jie, Jing</creatorcontrib><creatorcontrib>Luo, Jingjing</creatorcontrib><creatorcontrib>Xu, You</creatorcontrib><creatorcontrib>Sun, Hongying</creatorcontrib><creatorcontrib>Song, Lei</creatorcontrib><creatorcontrib>Li, Dan</creatorcontrib><creatorcontrib>Peng, Liping</creatorcontrib><creatorcontrib>Hua, Shucheng</creatorcontrib><title>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Betacoronavirus</subject><subject>Child</subject><subject>China - epidemiology</subject><subject>Coronavirus Infections - complications</subject><subject>Coronavirus Infections - epidemiology</subject><subject>Coronavirus Infections - virology</subject><subject>Cough - epidemiology</subject><subject>Cough - virology</subject><subject>COVID-19</subject><subject>Fatigue - epidemiology</subject><subject>Fatigue - virology</subject><subject>Female</subject><subject>Fever - epidemiology</subject><subject>Fever - virology</subject><subject>Hospitalization - statistics &amp; numerical data</subject><subject>Humans</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - virology</subject><subject>Lymphopenia - epidemiology</subject><subject>Lymphopenia - virology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Observational Study</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - complications</subject><subject>Pneumonia, Viral - epidemiology</subject><subject>Pneumonia, Viral - virology</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2</subject><subject>Severity of Illness Index</subject><subject>Tomography, X-Ray Computed - statistics &amp; numerical data</subject><subject>Young Adult</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkV1vFCEUhonR2LX6C0wMl23SqXwzeGHS7FZt06Y36i1hGKaDsrDCzDa98beL3bZ-cAE5nPc8kDwAvMboGCMl316ujtGfRShD8glYYE5Fw5VgT8Gi3vJGKsn2wItSviGEqSTsOdijlGDZtmIBfp5ufO_WPoV07a0J0MQe2uDjXWFHk42dXPZl8rbANECCsIIxbV3tppyi2fo8F9j74kxx8GB59fVs1WB1CH2E576SjuBy9NG8gyewd8Vmv5n81sEyzf3tS_BsMKG4V_fnPvjy4fTz8lNzcfXxbHly0VjKOW5MKzBDtDPUctXx1mDcEicIGVrpjBwYZQpLJjjvBBZcMMwJFaaziEuq-p7ug_c77mbu1q63Lk7ZBL3Jfm3yrU7G63870Y_6Om21FFIIpCrg4B6Q04_ZlUmvfbEuBBNdmosmTFCMeN1qlO6iNqdSshsen8FI_zanL1f6f3N16s3fP3yceVBVA2wXuEmhGinfw3zjsh6dCdN4x-NSkYagaggThJqquwr_Bcltols</recordid><startdate>20201120</startdate><enddate>20201120</enddate><creator>Liu, Han</creator><creator>Gao, Jinying</creator><creator>Wang, Yangyang</creator><creator>Jie, Jing</creator><creator>Luo, Jingjing</creator><creator>Xu, You</creator><creator>Sun, Hongying</creator><creator>Song, Lei</creator><creator>Li, Dan</creator><creator>Peng, Liping</creator><creator>Hua, Shucheng</creator><general>Lippincott Williams &amp; Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4531-1537</orcidid></search><sort><creationdate>20201120</creationdate><title>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</title><author>Liu, Han ; Gao, Jinying ; Wang, Yangyang ; Jie, Jing ; Luo, Jingjing ; Xu, You ; Sun, Hongying ; Song, Lei ; Li, Dan ; Peng, Liping ; Hua, Shucheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3551-a861403ba3c59b58a1182e622f87ea7f4349174655b61656415236abc05739dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Betacoronavirus</topic><topic>Child</topic><topic>China - epidemiology</topic><topic>Coronavirus Infections - complications</topic><topic>Coronavirus Infections - epidemiology</topic><topic>Coronavirus Infections - virology</topic><topic>Cough - epidemiology</topic><topic>Cough - virology</topic><topic>COVID-19</topic><topic>Fatigue - epidemiology</topic><topic>Fatigue - virology</topic><topic>Female</topic><topic>Fever - epidemiology</topic><topic>Fever - virology</topic><topic>Hospitalization - statistics &amp; numerical data</topic><topic>Humans</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - virology</topic><topic>Lymphopenia - epidemiology</topic><topic>Lymphopenia - virology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Observational Study</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - complications</topic><topic>Pneumonia, Viral - epidemiology</topic><topic>Pneumonia, Viral - virology</topic><topic>Retrospective Studies</topic><topic>SARS-CoV-2</topic><topic>Severity of Illness Index</topic><topic>Tomography, X-Ray Computed - statistics &amp; numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Han</creatorcontrib><creatorcontrib>Gao, Jinying</creatorcontrib><creatorcontrib>Wang, Yangyang</creatorcontrib><creatorcontrib>Jie, Jing</creatorcontrib><creatorcontrib>Luo, Jingjing</creatorcontrib><creatorcontrib>Xu, You</creatorcontrib><creatorcontrib>Sun, Hongying</creatorcontrib><creatorcontrib>Song, Lei</creatorcontrib><creatorcontrib>Li, Dan</creatorcontrib><creatorcontrib>Peng, Liping</creatorcontrib><creatorcontrib>Hua, Shucheng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Han</au><au>Gao, Jinying</au><au>Wang, Yangyang</au><au>Jie, Jing</au><au>Luo, Jingjing</au><au>Xu, You</au><au>Sun, Hongying</au><au>Song, Lei</au><au>Li, Dan</au><au>Peng, Liping</au><au>Hua, Shucheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2020-11-20</date><risdate>2020</risdate><volume>99</volume><issue>47</issue><spage>e23407</spage><epage>e23407</epage><pages>e23407-e23407</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.</abstract><cop>United States</cop><pub>Lippincott Williams &amp; Wilkins</pub><pmid>33217886</pmid><doi>10.1097/MD.0000000000023407</doi><orcidid>https://orcid.org/0000-0002-4531-1537</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0025-7974
ispartof Medicine (Baltimore), 2020-11, Vol.99 (47), p.e23407-e23407
issn 0025-7974
1536-5964
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7676609
source MEDLINE; DOAJ Directory of Open Access Journals; Wolters Kluwer Open Health; IngentaConnect Free/Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection
subjects Adolescent
Adult
Aged
Aged, 80 and over
Betacoronavirus
Child
China - epidemiology
Coronavirus Infections - complications
Coronavirus Infections - epidemiology
Coronavirus Infections - virology
Cough - epidemiology
Cough - virology
COVID-19
Fatigue - epidemiology
Fatigue - virology
Female
Fever - epidemiology
Fever - virology
Hospitalization - statistics & numerical data
Humans
Lung - diagnostic imaging
Lung - virology
Lymphopenia - epidemiology
Lymphopenia - virology
Male
Middle Aged
Observational Study
Pandemics
Pneumonia, Viral - complications
Pneumonia, Viral - epidemiology
Pneumonia, Viral - virology
Retrospective Studies
SARS-CoV-2
Severity of Illness Index
Tomography, X-Ray Computed - statistics & numerical data
Young Adult
title Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T13%3A06%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Epidemiological%20and%20clinical%20characteristics%20of%202019%20novel%20coronavirus%20disease%20(COVID-19)%20in%20Jilin,%20China:%20A%20descriptive%20study&rft.jtitle=Medicine%20(Baltimore)&rft.au=Liu,%20Han&rft.date=2020-11-20&rft.volume=99&rft.issue=47&rft.spage=e23407&rft.epage=e23407&rft.pages=e23407-e23407&rft.issn=0025-7974&rft.eissn=1536-5964&rft_id=info:doi/10.1097/MD.0000000000023407&rft_dat=%3Cproquest_pubme%3E2463105631%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2463105631&rft_id=info:pmid/33217886&rfr_iscdi=true