Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study
Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively i...
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Veröffentlicht in: | Medicine (Baltimore) 2020-11, Vol.99 (47), p.e23407-e23407 |
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creator | Liu, Han Gao, Jinying Wang, Yangyang Jie, Jing Luo, Jingjing Xu, You Sun, Hongying Song, Lei Li, Dan Peng, Liping Hua, Shucheng |
description | Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge. |
doi_str_mv | 10.1097/MD.0000000000023407 |
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To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000023407</identifier><identifier>PMID: 33217886</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; Child ; China - epidemiology ; Coronavirus Infections - complications ; Coronavirus Infections - epidemiology ; Coronavirus Infections - virology ; Cough - epidemiology ; Cough - virology ; COVID-19 ; Fatigue - epidemiology ; Fatigue - virology ; Female ; Fever - epidemiology ; Fever - virology ; Hospitalization - statistics & numerical data ; Humans ; Lung - diagnostic imaging ; Lung - virology ; Lymphopenia - epidemiology ; Lymphopenia - virology ; Male ; Middle Aged ; Observational Study ; Pandemics ; Pneumonia, Viral - complications ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - virology ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index ; Tomography, X-Ray Computed - statistics & numerical data ; Young Adult</subject><ispartof>Medicine (Baltimore), 2020-11, Vol.99 (47), p.e23407-e23407</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3551-a861403ba3c59b58a1182e622f87ea7f4349174655b61656415236abc05739dd3</cites><orcidid>0000-0002-4531-1537</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676609/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676609/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33217886$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Han</creatorcontrib><creatorcontrib>Gao, Jinying</creatorcontrib><creatorcontrib>Wang, Yangyang</creatorcontrib><creatorcontrib>Jie, Jing</creatorcontrib><creatorcontrib>Luo, Jingjing</creatorcontrib><creatorcontrib>Xu, You</creatorcontrib><creatorcontrib>Sun, Hongying</creatorcontrib><creatorcontrib>Song, Lei</creatorcontrib><creatorcontrib>Li, Dan</creatorcontrib><creatorcontrib>Peng, Liping</creatorcontrib><creatorcontrib>Hua, Shucheng</creatorcontrib><title>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Betacoronavirus</subject><subject>Child</subject><subject>China - epidemiology</subject><subject>Coronavirus Infections - complications</subject><subject>Coronavirus Infections - epidemiology</subject><subject>Coronavirus Infections - virology</subject><subject>Cough - epidemiology</subject><subject>Cough - virology</subject><subject>COVID-19</subject><subject>Fatigue - epidemiology</subject><subject>Fatigue - virology</subject><subject>Female</subject><subject>Fever - epidemiology</subject><subject>Fever - virology</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - virology</subject><subject>Lymphopenia - epidemiology</subject><subject>Lymphopenia - virology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Observational Study</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - complications</subject><subject>Pneumonia, Viral - epidemiology</subject><subject>Pneumonia, Viral - virology</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2</subject><subject>Severity of Illness Index</subject><subject>Tomography, X-Ray Computed - statistics & numerical data</subject><subject>Young Adult</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkV1vFCEUhonR2LX6C0wMl23SqXwzeGHS7FZt06Y36i1hGKaDsrDCzDa98beL3bZ-cAE5nPc8kDwAvMboGCMl316ujtGfRShD8glYYE5Fw5VgT8Gi3vJGKsn2wItSviGEqSTsOdijlGDZtmIBfp5ufO_WPoV07a0J0MQe2uDjXWFHk42dXPZl8rbANECCsIIxbV3tppyi2fo8F9j74kxx8GB59fVs1WB1CH2E576SjuBy9NG8gyewd8Vmv5n81sEyzf3tS_BsMKG4V_fnPvjy4fTz8lNzcfXxbHly0VjKOW5MKzBDtDPUctXx1mDcEicIGVrpjBwYZQpLJjjvBBZcMMwJFaaziEuq-p7ug_c77mbu1q63Lk7ZBL3Jfm3yrU7G63870Y_6Om21FFIIpCrg4B6Q04_ZlUmvfbEuBBNdmosmTFCMeN1qlO6iNqdSshsen8FI_zanL1f6f3N16s3fP3yceVBVA2wXuEmhGinfw3zjsh6dCdN4x-NSkYagaggThJqquwr_Bcltols</recordid><startdate>20201120</startdate><enddate>20201120</enddate><creator>Liu, Han</creator><creator>Gao, Jinying</creator><creator>Wang, Yangyang</creator><creator>Jie, Jing</creator><creator>Luo, Jingjing</creator><creator>Xu, You</creator><creator>Sun, Hongying</creator><creator>Song, Lei</creator><creator>Li, Dan</creator><creator>Peng, Liping</creator><creator>Hua, Shucheng</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4531-1537</orcidid></search><sort><creationdate>20201120</creationdate><title>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</title><author>Liu, Han ; Gao, Jinying ; Wang, Yangyang ; Jie, Jing ; Luo, Jingjing ; Xu, You ; Sun, Hongying ; Song, Lei ; Li, Dan ; Peng, Liping ; Hua, Shucheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3551-a861403ba3c59b58a1182e622f87ea7f4349174655b61656415236abc05739dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Betacoronavirus</topic><topic>Child</topic><topic>China - epidemiology</topic><topic>Coronavirus Infections - complications</topic><topic>Coronavirus Infections - epidemiology</topic><topic>Coronavirus Infections - virology</topic><topic>Cough - epidemiology</topic><topic>Cough - virology</topic><topic>COVID-19</topic><topic>Fatigue - epidemiology</topic><topic>Fatigue - virology</topic><topic>Female</topic><topic>Fever - epidemiology</topic><topic>Fever - virology</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - virology</topic><topic>Lymphopenia - epidemiology</topic><topic>Lymphopenia - virology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Observational Study</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - complications</topic><topic>Pneumonia, Viral - epidemiology</topic><topic>Pneumonia, Viral - virology</topic><topic>Retrospective Studies</topic><topic>SARS-CoV-2</topic><topic>Severity of Illness Index</topic><topic>Tomography, X-Ray Computed - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Han</creatorcontrib><creatorcontrib>Gao, Jinying</creatorcontrib><creatorcontrib>Wang, Yangyang</creatorcontrib><creatorcontrib>Jie, Jing</creatorcontrib><creatorcontrib>Luo, Jingjing</creatorcontrib><creatorcontrib>Xu, You</creatorcontrib><creatorcontrib>Sun, Hongying</creatorcontrib><creatorcontrib>Song, Lei</creatorcontrib><creatorcontrib>Li, Dan</creatorcontrib><creatorcontrib>Peng, Liping</creatorcontrib><creatorcontrib>Hua, Shucheng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Han</au><au>Gao, Jinying</au><au>Wang, Yangyang</au><au>Jie, Jing</au><au>Luo, Jingjing</au><au>Xu, You</au><au>Sun, Hongying</au><au>Song, Lei</au><au>Li, Dan</au><au>Peng, Liping</au><au>Hua, Shucheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2020-11-20</date><risdate>2020</risdate><volume>99</volume><issue>47</issue><spage>e23407</spage><epage>e23407</epage><pages>e23407-e23407</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>33217886</pmid><doi>10.1097/MD.0000000000023407</doi><orcidid>https://orcid.org/0000-0002-4531-1537</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Betacoronavirus Child China - epidemiology Coronavirus Infections - complications Coronavirus Infections - epidemiology Coronavirus Infections - virology Cough - epidemiology Cough - virology COVID-19 Fatigue - epidemiology Fatigue - virology Female Fever - epidemiology Fever - virology Hospitalization - statistics & numerical data Humans Lung - diagnostic imaging Lung - virology Lymphopenia - epidemiology Lymphopenia - virology Male Middle Aged Observational Study Pandemics Pneumonia, Viral - complications Pneumonia, Viral - epidemiology Pneumonia, Viral - virology Retrospective Studies SARS-CoV-2 Severity of Illness Index Tomography, X-Ray Computed - statistics & numerical data Young Adult |
title | Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study |
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