A large-scale genome-wide association study meta-analysis of cannabis use disorder

Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50–70%) and is associated with negative outcomes, including increased risk of psychopathology. The aim of the study was to conduct a large genome-wide association study (GWAS)...

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Veröffentlicht in:	The Lancet. Psychiatry 2020-12, Vol.7 (12), p.1032-1045
Hauptverfasser:	Johnson, Emma C, Demontis, Ditte, Thorgeirsson, Thorgeir E, Walters, Raymond K, Polimanti, Renato, Hatoum, Alexander S, Clarke, Toni-Kim, Baranger, David A A, Wedow, Robbee, Bacanu, Silviu-Alin, Brown, Sandra A, Degenhardt, Louisa, Goate, Alison M, Gordon, Scott D, Lind, Penelope A, McQueen, Matthew B, Pearson, John F, Peterson, Roseann E, Reynolds, Maureen D, Saccone, Nancy L, Sherva, Richard, Tyrfingsson, Thorarinn, Wall, Tamara L, Werge, Thomas, Wetherill, Leah, Wright, Margaret J, Zellers, Stephanie, Boardman, Jason D, Copeland, William E, Gillespie, Nathan A, Grucza, Richard A, Kendler, Kenneth S, Maes, Hermine H, McIntosh, Andrew M, Porjesz, Bernice, Vanyukov, Michael M, Vrieze, Scott, Walters, Raymond, Johnson, Emma, He, June, Adkins, Amy, Biernacka, Joanna, Bigdeli, Tim, Chen, Li-Shiun, Docherty, Anna, Edwards, Alexis, Gordon, Scott, Hartmann, Annette, Hartz, Sarah, Hodgkinson, Colin, Hottenga, Jouke, Lahti-Pulkkinen, Marius, Ligthart, Lannie, Maher, Brion, McQueen, Matthew, Meyers, Jacquelyn, Milaneschi, Yuri, Palviainen, Teemu, Pearson, John, Ripatti, Samuli, Saccone, Nancy, Thomas, Nathaniel, Wang, Jen-Chyong, Choi, Doo-Sup, Culverhouse, Robert, Dahmen, Norbert, Domingue, Benjamin, Frye, Mark, Gäbel, Wolfgang, Mann, Karl, Nurnberger, John, Reynolds, Maureen, Schuckit, Marc, Soyka, Michael, Wodarz, Norbert, Zill, Peter, Boomsma, Dorret, Bierut, Laura, Bucholz, Kathleen, Cichon, Sven, Costello, E. Jane, Diazgranados, Nancy, Dick, Danielle, Goldman, David, Heath, Andrew, Hesselbrock, Victor, Hewitt, John, Hopfer, Christian, Kendler, Kenneth, Madden, Pamela, Magnusson, Patrik, Medland, Sarah, Rietschel, Marcella, Riley, Brien, Silberg, Judy, Stefansson, Kari
Format:	Artikel
Sprache:	eng
Schlagworte:	Genome-Wide Association Study Humans Marijuana Abuse - genetics Polymorphism, Single Nucleotide Risk
Online-Zugang:	Volltext
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