Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin

Cell differentiation and function are regulated across multiple layers of gene regulation, including modulation of gene expression by changes in chromatin accessibility. However, differentiation is an asynchronous process precluding a temporal understanding of regulatory events leading to cell fate...

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Veröffentlicht in:Cell 2020-11, Vol.183 (4), p.1103-1116.e20
Hauptverfasser: Ma, Sai, Zhang, Bing, LaFave, Lindsay M., Earl, Andrew S., Chiang, Zachary, Hu, Yan, Ding, Jiarui, Brack, Alison, Kartha, Vinay K., Tay, Tristan, Law, Travis, Lareau, Caleb, Hsu, Ya-Chieh, Regev, Aviv, Buenrostro, Jason D.
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Sprache:eng
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