Targeting DNA Damage Response in Prostate and Breast Cancer

Steroid hormone signaling induces vast gene expression programs which necessitate the local formation of transcription factories at regulatory regions and large-scale alterations of the genome architecture to allow communication among distantly related cis-acting regions. This involves major stress...

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Veröffentlicht in:	International journal of molecular sciences 2020-11, Vol.21 (21), p.8273
Hauptverfasser:	Wengner, Antje M, Scholz, Arne, Haendler, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - genetics Breast Neoplasms - pathology Breast Neoplasms - therapy DNA Damage - physiology DNA Repair - genetics Female Humans Male Medical Oncology - methods Medical Oncology - trends Molecular Targeted Therapy - methods Molecular Targeted Therapy - trends Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Review Signal Transduction - genetics
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