Prevalence of diabetes, management and outcomes among Covid-19 adult patients admitted in a specialized tertiary hospital in Riyadh, Saudi Arabia
This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as perthe Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed...
Gespeichert in:
| Veröffentlicht in: | Diabetes research and clinical practice 2021-02, Vol.172, p.108538-108538, Article 108538 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 108538 |
|---|---|
| container_issue | |
| container_start_page | 108538 |
| container_title | Diabetes research and clinical practice |
| container_volume | 172 |
| creator | Sheshah, Eman Sabico, Shaun Albakr, Rashed M. Sultan, Anmar A. Alghamdi, Khalaf S. Al Madani, Khaled Alotair, Hadil A. Al-Daghri, Nasser M. |
| description | This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as perthe Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed SARS-CoV2 infection and admitted in King Salman Hospital (KSH) from May 1 to July 31, 2020 were included. Medical history, management and outcomes were noted. Males significantly outnumber females (259 versus 41). South Asians comprise 41% of all admitted patients. Mortality rate was 10% and highest among Saudi males (28.9%). Type 2 diabetes mellitus (T2DM) was the most common comorbidity (45.7%). Almost all patients (99%) had pneumonia. Patients > 50 years were three times more likely to die (confidence interval, CI 1.3–6.9; p = 0.01) from Covid-19. Congestive heart failure (odds ratio OR 19.4, CI-1.5–260.0; p = 0.02) and acute kidney injury (OR 11.7, CI-4.7–28.6; p |
| doi_str_mv | 10.1016/j.diabres.2020.108538 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7661919</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0168822720307956</els_id><sourcerecordid>2460998574</sourcerecordid><originalsourceid>FETCH-LOGICAL-c467t-1c234d7780e6fe999bc56aedac6640772687c275a6c20c5c42e47762b6a6d5cf3</originalsourceid><addsrcrecordid>eNqFkd2O0zAQhS0EYsvCI4B8ycWmOE5ixzegVbX8SCuB-Lm2JvakdZXExXYqLW_BG-PQsoIrrmzNfHPmaA4hz0u2LlkpXu3X1kEXMK4540utbar2AVmVreRFy7l8SFaZa3__L8iTGPeMMVHVzWNyUVVlq6RiK_LzU8AjDDgZpL6niyYmjFd0hAm2OOKUKEyW-jkZP2KkMPppSzf-6GxRKgp2HhI9QHKZzF07upTQUjdRoPGAxsHgfuRCwpAchDu68_HgEgwL8tndgd1d0S8wW0evA3QOnpJHPQwRn53fS_Lt7c3Xzfvi9uO7D5vr28LUQqaiNLyqrZQtQ9GjUqozjQC0YISomZRctNJw2YAwnJnG1BxrKQXvBAjbmL66JK9Puoe5G9Ga7D_AoA_Bjdmm9uD0v53J7fTWH7UUolSlygIvzwLBf58xJj26aHAYYEI_R81rwZRqG1lntDmhJvgYA_b3a0qmlzj1Xp_j1Euc-hRnnnvxt8f7qT_5ZeDNCcB8qaPDoKNxS5jWBTRJW-_-s-IXz3G2tw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2460998574</pqid></control><display><type>article</type><title>Prevalence of diabetes, management and outcomes among Covid-19 adult patients admitted in a specialized tertiary hospital in Riyadh, Saudi Arabia</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Sheshah, Eman ; Sabico, Shaun ; Albakr, Rashed M. ; Sultan, Anmar A. ; Alghamdi, Khalaf S. ; Al Madani, Khaled ; Alotair, Hadil A. ; Al-Daghri, Nasser M.</creator><creatorcontrib>Sheshah, Eman ; Sabico, Shaun ; Albakr, Rashed M. ; Sultan, Anmar A. ; Alghamdi, Khalaf S. ; Al Madani, Khaled ; Alotair, Hadil A. ; Al-Daghri, Nasser M.</creatorcontrib><description>This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as perthe Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed SARS-CoV2 infection and admitted in King Salman Hospital (KSH) from May 1 to July 31, 2020 were included. Medical history, management and outcomes were noted. Males significantly outnumber females (259 versus 41). South Asians comprise 41% of all admitted patients. Mortality rate was 10% and highest among Saudi males (28.9%). Type 2 diabetes mellitus (T2DM) was the most common comorbidity (45.7%). Almost all patients (99%) had pneumonia. Patients > 50 years were three times more likely to die (confidence interval, CI 1.3–6.9; p = 0.01) from Covid-19. Congestive heart failure (odds ratio OR 19.4, CI-1.5–260.0; p = 0.02) and acute kidney injury (OR 11.7, CI-4.7–28.6; p < 0.001) were significantly associated with higher mortality. Dexamethasone use significantly improved the final outcome based on net reclassification improvement (NRI) and integrated discrimination improvement (IDI) (p < 0.05). In this single-center study, T2DM was very common among hospitalized Covid-19 patients. Patients > 50 years, those with congestive heart failure and acute kidney injury are at higher risk for worse Covid-19 outcome.</description><identifier>ISSN: 0168-8227</identifier><identifier>EISSN: 1872-8227</identifier><identifier>DOI: 10.1016/j.diabres.2020.108538</identifier><identifier>PMID: 33189790</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Comorbidity ; Covid-19 ; COVID-19 - epidemiology ; COVID-19 - therapy ; Diabetes Mellitus, Type 2 - epidemiology ; Disease Management ; Female ; Hospitalization - trends ; Hospitals, Special - statistics & numerical data ; Humans ; Male ; Middle Aged ; Prevalence ; Retrospective Studies ; SARS-CoV-2 ; Saudi Arabia ; Saudi Arabia - epidemiology ; South Asians ; Tertiary Care Centers - statistics & numerical data ; Type 2 Diabetes Mellitus ; Young Adult</subject><ispartof>Diabetes research and clinical practice, 2021-02, Vol.172, p.108538-108538, Article 108538</ispartof><rights>2020 The Author(s)</rights><rights>Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.</rights><rights>2020 The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c467t-1c234d7780e6fe999bc56aedac6640772687c275a6c20c5c42e47762b6a6d5cf3</citedby><cites>FETCH-LOGICAL-c467t-1c234d7780e6fe999bc56aedac6640772687c275a6c20c5c42e47762b6a6d5cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0168822720307956$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33189790$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sheshah, Eman</creatorcontrib><creatorcontrib>Sabico, Shaun</creatorcontrib><creatorcontrib>Albakr, Rashed M.</creatorcontrib><creatorcontrib>Sultan, Anmar A.</creatorcontrib><creatorcontrib>Alghamdi, Khalaf S.</creatorcontrib><creatorcontrib>Al Madani, Khaled</creatorcontrib><creatorcontrib>Alotair, Hadil A.</creatorcontrib><creatorcontrib>Al-Daghri, Nasser M.</creatorcontrib><title>Prevalence of diabetes, management and outcomes among Covid-19 adult patients admitted in a specialized tertiary hospital in Riyadh, Saudi Arabia</title><title>Diabetes research and clinical practice</title><addtitle>Diabetes Res Clin Pract</addtitle><description>This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as perthe Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed SARS-CoV2 infection and admitted in King Salman Hospital (KSH) from May 1 to July 31, 2020 were included. Medical history, management and outcomes were noted. Males significantly outnumber females (259 versus 41). South Asians comprise 41% of all admitted patients. Mortality rate was 10% and highest among Saudi males (28.9%). Type 2 diabetes mellitus (T2DM) was the most common comorbidity (45.7%). Almost all patients (99%) had pneumonia. Patients > 50 years were three times more likely to die (confidence interval, CI 1.3–6.9; p = 0.01) from Covid-19. Congestive heart failure (odds ratio OR 19.4, CI-1.5–260.0; p = 0.02) and acute kidney injury (OR 11.7, CI-4.7–28.6; p < 0.001) were significantly associated with higher mortality. Dexamethasone use significantly improved the final outcome based on net reclassification improvement (NRI) and integrated discrimination improvement (IDI) (p < 0.05). In this single-center study, T2DM was very common among hospitalized Covid-19 patients. Patients > 50 years, those with congestive heart failure and acute kidney injury are at higher risk for worse Covid-19 outcome.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Comorbidity</subject><subject>Covid-19</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - therapy</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Disease Management</subject><subject>Female</subject><subject>Hospitalization - trends</subject><subject>Hospitals, Special - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2</subject><subject>Saudi Arabia</subject><subject>Saudi Arabia - epidemiology</subject><subject>South Asians</subject><subject>Tertiary Care Centers - statistics & numerical data</subject><subject>Type 2 Diabetes Mellitus</subject><subject>Young Adult</subject><issn>0168-8227</issn><issn>1872-8227</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkd2O0zAQhS0EYsvCI4B8ycWmOE5ixzegVbX8SCuB-Lm2JvakdZXExXYqLW_BG-PQsoIrrmzNfHPmaA4hz0u2LlkpXu3X1kEXMK4540utbar2AVmVreRFy7l8SFaZa3__L8iTGPeMMVHVzWNyUVVlq6RiK_LzU8AjDDgZpL6niyYmjFd0hAm2OOKUKEyW-jkZP2KkMPppSzf-6GxRKgp2HhI9QHKZzF07upTQUjdRoPGAxsHgfuRCwpAchDu68_HgEgwL8tndgd1d0S8wW0evA3QOnpJHPQwRn53fS_Lt7c3Xzfvi9uO7D5vr28LUQqaiNLyqrZQtQ9GjUqozjQC0YISomZRctNJw2YAwnJnG1BxrKQXvBAjbmL66JK9Puoe5G9Ga7D_AoA_Bjdmm9uD0v53J7fTWH7UUolSlygIvzwLBf58xJj26aHAYYEI_R81rwZRqG1lntDmhJvgYA_b3a0qmlzj1Xp_j1Euc-hRnnnvxt8f7qT_5ZeDNCcB8qaPDoKNxS5jWBTRJW-_-s-IXz3G2tw</recordid><startdate>20210201</startdate><enddate>20210201</enddate><creator>Sheshah, Eman</creator><creator>Sabico, Shaun</creator><creator>Albakr, Rashed M.</creator><creator>Sultan, Anmar A.</creator><creator>Alghamdi, Khalaf S.</creator><creator>Al Madani, Khaled</creator><creator>Alotair, Hadil A.</creator><creator>Al-Daghri, Nasser M.</creator><general>Elsevier B.V</general><general>The Author(s). Published by Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210201</creationdate><title>Prevalence of diabetes, management and outcomes among Covid-19 adult patients admitted in a specialized tertiary hospital in Riyadh, Saudi Arabia</title><author>Sheshah, Eman ; Sabico, Shaun ; Albakr, Rashed M. ; Sultan, Anmar A. ; Alghamdi, Khalaf S. ; Al Madani, Khaled ; Alotair, Hadil A. ; Al-Daghri, Nasser M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c467t-1c234d7780e6fe999bc56aedac6640772687c275a6c20c5c42e47762b6a6d5cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Comorbidity</topic><topic>Covid-19</topic><topic>COVID-19 - epidemiology</topic><topic>COVID-19 - therapy</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Disease Management</topic><topic>Female</topic><topic>Hospitalization - trends</topic><topic>Hospitals, Special - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Retrospective Studies</topic><topic>SARS-CoV-2</topic><topic>Saudi Arabia</topic><topic>Saudi Arabia - epidemiology</topic><topic>South Asians</topic><topic>Tertiary Care Centers - statistics & numerical data</topic><topic>Type 2 Diabetes Mellitus</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sheshah, Eman</creatorcontrib><creatorcontrib>Sabico, Shaun</creatorcontrib><creatorcontrib>Albakr, Rashed M.</creatorcontrib><creatorcontrib>Sultan, Anmar A.</creatorcontrib><creatorcontrib>Alghamdi, Khalaf S.</creatorcontrib><creatorcontrib>Al Madani, Khaled</creatorcontrib><creatorcontrib>Alotair, Hadil A.</creatorcontrib><creatorcontrib>Al-Daghri, Nasser M.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Diabetes research and clinical practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sheshah, Eman</au><au>Sabico, Shaun</au><au>Albakr, Rashed M.</au><au>Sultan, Anmar A.</au><au>Alghamdi, Khalaf S.</au><au>Al Madani, Khaled</au><au>Alotair, Hadil A.</au><au>Al-Daghri, Nasser M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of diabetes, management and outcomes among Covid-19 adult patients admitted in a specialized tertiary hospital in Riyadh, Saudi Arabia</atitle><jtitle>Diabetes research and clinical practice</jtitle><addtitle>Diabetes Res Clin Pract</addtitle><date>2021-02-01</date><risdate>2021</risdate><volume>172</volume><spage>108538</spage><epage>108538</epage><pages>108538-108538</pages><artnum>108538</artnum><issn>0168-8227</issn><eissn>1872-8227</eissn><abstract>This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as perthe Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed SARS-CoV2 infection and admitted in King Salman Hospital (KSH) from May 1 to July 31, 2020 were included. Medical history, management and outcomes were noted. Males significantly outnumber females (259 versus 41). South Asians comprise 41% of all admitted patients. Mortality rate was 10% and highest among Saudi males (28.9%). Type 2 diabetes mellitus (T2DM) was the most common comorbidity (45.7%). Almost all patients (99%) had pneumonia. Patients > 50 years were three times more likely to die (confidence interval, CI 1.3–6.9; p = 0.01) from Covid-19. Congestive heart failure (odds ratio OR 19.4, CI-1.5–260.0; p = 0.02) and acute kidney injury (OR 11.7, CI-4.7–28.6; p < 0.001) were significantly associated with higher mortality. Dexamethasone use significantly improved the final outcome based on net reclassification improvement (NRI) and integrated discrimination improvement (IDI) (p < 0.05). In this single-center study, T2DM was very common among hospitalized Covid-19 patients. Patients > 50 years, those with congestive heart failure and acute kidney injury are at higher risk for worse Covid-19 outcome.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>33189790</pmid><doi>10.1016/j.diabres.2020.108538</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0168-8227 |
| ispartof | Diabetes research and clinical practice, 2021-02, Vol.172, p.108538-108538, Article 108538 |
| issn | 0168-8227 1872-8227 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7661919 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Aged Aged, 80 and over Comorbidity Covid-19 COVID-19 - epidemiology COVID-19 - therapy Diabetes Mellitus, Type 2 - epidemiology Disease Management Female Hospitalization - trends Hospitals, Special - statistics & numerical data Humans Male Middle Aged Prevalence Retrospective Studies SARS-CoV-2 Saudi Arabia Saudi Arabia - epidemiology South Asians Tertiary Care Centers - statistics & numerical data Type 2 Diabetes Mellitus Young Adult |
| title | Prevalence of diabetes, management and outcomes among Covid-19 adult patients admitted in a specialized tertiary hospital in Riyadh, Saudi Arabia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T05%3A40%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20of%20diabetes,%20management%20and%20outcomes%20among%20Covid-19%20adult%20patients%20admitted%20in%20a%20specialized%20tertiary%20hospital%20in%20Riyadh,%20Saudi%20Arabia&rft.jtitle=Diabetes%20research%20and%20clinical%20practice&rft.au=Sheshah,%20Eman&rft.date=2021-02-01&rft.volume=172&rft.spage=108538&rft.epage=108538&rft.pages=108538-108538&rft.artnum=108538&rft.issn=0168-8227&rft.eissn=1872-8227&rft_id=info:doi/10.1016/j.diabres.2020.108538&rft_dat=%3Cproquest_pubme%3E2460998574%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2460998574&rft_id=info:pmid/33189790&rft_els_id=S0168822720307956&rfr_iscdi=true |