The Pex3-Inp1 complex tethers yeast peroxisomes to the plasma membrane

A subset of peroxisomes is retained at the mother cell cortex by the Pex3-Inp1 complex. We identify Inp1 as the first known plasma membrane-peroxisome (PM-PER) tether by demonstrating that Inp1 meets the predefined criteria that a contact site tether protein must adhere to. We show that Inp1 is pres...

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Veröffentlicht in:	The Journal of cell biology 2020-10, Vol.219 (10)
Hauptverfasser:	Hulmes, Georgia E, Hutchinson, John D, Dahan, Noa, Nuttall, James M, Allwood, Ellen G, Ayscough, Kathryn R, Hettema, Ewald H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence - genetics Biochemistry Cell Membrane - genetics Membrane and Lipid Biology Membrane Proteins - genetics Microbiology Multiprotein Complexes - genetics Organelles Peroxins - genetics Peroxisomes - genetics Phosphatidylinositols - genetics Protein Binding - genetics Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - genetics
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