Asthma in COVID-19 patients: An extra chain fitting around the neck?
The novel coronavirus disease 2019 (COVID-19) has rapidly spread across the globe. Pre-existing comorbidities have been found to have a dramatic effect on the disease course. We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients. We conducted a multi-...
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| Veröffentlicht in: | Respiratory medicine 2020-12, Vol.175, p.106205-106205, Article 106205 |
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| creator | Hussein, Mohammad H. Toraih, Eman A. Attia, Abdallah S. Burley, Nicholas Zhang, Allen D. Roos, Jackson Houghton, August Aniemeka, Nedum Omar, Mahmoud Aboueisha, Mohamed Shama, Mohamed A. Duchesne, Juan Kandil, Emad |
| description | The novel coronavirus disease 2019 (COVID-19) has rapidly spread across the globe. Pre-existing comorbidities have been found to have a dramatic effect on the disease course. We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients.
We conducted a multi-center retrospective study of positively confirmed COVID-19 patients. The primary outcome of interest was in-hospital mortality. Secondary outcomes were the Intensive Care Unit (ICU) admission, intubation, mechanical ventilation, and length of hospital stay.
A total of 502 COVID-19 adult patients (72 asthma and 430 non-asthma cohorts) with mean age of 60.7 years were included in the study. The frequency of asthma in hospitalized cohorts was 14.3%. Univariate analysis revealed that asthma patients were more likely to be obese (75% versus 54.2%, p = 0.001), with a higher frequency of intubation (40.3% versus 27.8%, p = 0.036), and required a longer duration of hospitalization (15.1 ± 12.5 versus 11.5 ± 10.6, p = 0.015). After adjustment, multivariable analysis showed that asthmatic patients were not associated with higher risk of ICU admission (OR = 1.81, 95%CI = 0.98–3.09, p = 0.06), endotracheal intubation (OR = 1.77, 95%CI = 0.99–3.04, p = 0.06) or complications (OR = 1.37, 95%CI = 0.82–2.31, p = 0.23). Asthmatic patients were not associated with higher odds of prolonged hospital length of stay (OR = 1.48, 95%CI = 0.82–2.66, p = 0.20) or with ICU stay (OR = 0.76, 95%CI = 0.28–2.02, p = 0.58). Kaplan-Meier curve showed no significant difference in the overall survival of the two groups (p = 0.65).
Despite the increased prevalence of hospitalization in elder asthmatic COVID-19 patients, after adjustment for other variables, it was neither associated with increased severity nor worse outcomes.
[Display omitted]
•Asthma is more prevalent in COVID-19 cohort than in the general population.•Asthma was neither associated with disease severity nor negative outcomes.•Asthma does not imply a worse outcome as compared to non-asthmatics. |
| doi_str_mv | 10.1016/j.rmed.2020.106205 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7657611</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0954611120303450</els_id><sourcerecordid>2464599269</sourcerecordid><originalsourceid>FETCH-LOGICAL-c549t-6f26c9aa1393add365d47c5d678226c9ef2933a16951d9a7d6d6e3798dbc43c63</originalsourceid><addsrcrecordid>eNp9kU1rGzEQhkVpSZykf6CHIugll3X0vVYpCcb5qMHgS9urkCVtLNfWOpI2JP8-WuyYtIecBJpnXmbmAeALRkOMsLhYDePG2SFBpP8QBPEPYIA5JRVFgn0EAyQ5qwTG-BicpLRCCEnG0BE4ppTgmtPRAFyPU15uNPQBTuZ_ptcVlnCrs3chp-9wHKB7ylFDs9SFaHzOPtxDHdsuWJiXDgZn_l6dgU-NXif3ef-egt-3N78mP6vZ_G46Gc8qw5nMlWiIMFJrTCXV1lLBLasNt6Iekb7iGiIp1VhIjq3UtRVWOFrLkV0YRo2gp-Byl7vtFmVzU4aMeq220W90fFat9urfSvBLdd8-qlrwutyhBJzvA2L70LmU1cYn49ZrHVzbJUWYoBiNJEYF_fYfumq7GMp6PcW4lETIQpEdZWKbUnTNYRiMVC9JrVQvSfWS1E5Safr6do1Dy6uVAvzYAa4c89G7qJIpRoyzPjqTlW39e_kvs8KgxQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2464599269</pqid></control><display><type>article</type><title>Asthma in COVID-19 patients: An extra chain fitting around the neck?</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Hussein, Mohammad H. ; Toraih, Eman A. ; Attia, Abdallah S. ; Burley, Nicholas ; Zhang, Allen D. ; Roos, Jackson ; Houghton, August ; Aniemeka, Nedum ; Omar, Mahmoud ; Aboueisha, Mohamed ; Shama, Mohamed A. ; Duchesne, Juan ; Kandil, Emad</creator><creatorcontrib>Hussein, Mohammad H. ; Toraih, Eman A. ; Attia, Abdallah S. ; Burley, Nicholas ; Zhang, Allen D. ; Roos, Jackson ; Houghton, August ; Aniemeka, Nedum ; Omar, Mahmoud ; Aboueisha, Mohamed ; Shama, Mohamed A. ; Duchesne, Juan ; Kandil, Emad</creatorcontrib><description>The novel coronavirus disease 2019 (COVID-19) has rapidly spread across the globe. Pre-existing comorbidities have been found to have a dramatic effect on the disease course. We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients.
We conducted a multi-center retrospective study of positively confirmed COVID-19 patients. The primary outcome of interest was in-hospital mortality. Secondary outcomes were the Intensive Care Unit (ICU) admission, intubation, mechanical ventilation, and length of hospital stay.
A total of 502 COVID-19 adult patients (72 asthma and 430 non-asthma cohorts) with mean age of 60.7 years were included in the study. The frequency of asthma in hospitalized cohorts was 14.3%. Univariate analysis revealed that asthma patients were more likely to be obese (75% versus 54.2%, p = 0.001), with a higher frequency of intubation (40.3% versus 27.8%, p = 0.036), and required a longer duration of hospitalization (15.1 ± 12.5 versus 11.5 ± 10.6, p = 0.015). After adjustment, multivariable analysis showed that asthmatic patients were not associated with higher risk of ICU admission (OR = 1.81, 95%CI = 0.98–3.09, p = 0.06), endotracheal intubation (OR = 1.77, 95%CI = 0.99–3.04, p = 0.06) or complications (OR = 1.37, 95%CI = 0.82–2.31, p = 0.23). Asthmatic patients were not associated with higher odds of prolonged hospital length of stay (OR = 1.48, 95%CI = 0.82–2.66, p = 0.20) or with ICU stay (OR = 0.76, 95%CI = 0.28–2.02, p = 0.58). Kaplan-Meier curve showed no significant difference in the overall survival of the two groups (p = 0.65).
Despite the increased prevalence of hospitalization in elder asthmatic COVID-19 patients, after adjustment for other variables, it was neither associated with increased severity nor worse outcomes.
[Display omitted]
•Asthma is more prevalent in COVID-19 cohort than in the general population.•Asthma was neither associated with disease severity nor negative outcomes.•Asthma does not imply a worse outcome as compared to non-asthmatics.</description><identifier>ISSN: 0954-6111</identifier><identifier>EISSN: 1532-3064</identifier><identifier>DOI: 10.1016/j.rmed.2020.106205</identifier><identifier>PMID: 33217538</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Aged ; Aged, 80 and over ; Asthma ; Asthma - complications ; Asthma - epidemiology ; Case-Control Studies ; Chronic lung disease ; Comorbidity ; Complications ; Coronaviruses ; COVID-19 ; COVID-19 - complications ; COVID-19 - diagnosis ; COVID-19 - epidemiology ; COVID-19 - virology ; Disease Progression ; Hospital Mortality - trends ; Hospitalization - statistics & numerical data ; Humans ; Intensive Care Units - statistics & numerical data ; Intubation ; Intubation, Intratracheal - statistics & numerical data ; Length of Stay - statistics & numerical data ; Mechanical ventilation ; Medical prognosis ; Middle Aged ; Obesity ; Prevalence ; Prognosis ; Respiration, Artificial - statistics & numerical data ; Retrospective Studies ; SARS-CoV-2 ; SARS-CoV-2 - genetics ; Ventilation</subject><ispartof>Respiratory medicine, 2020-12, Vol.175, p.106205-106205, Article 106205</ispartof><rights>2020 Elsevier Ltd</rights><rights>Copyright © 2020 Elsevier Ltd. All rights reserved.</rights><rights>2020. Elsevier Ltd</rights><rights>2020 Elsevier Ltd. All rights reserved. 2020 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c549t-6f26c9aa1393add365d47c5d678226c9ef2933a16951d9a7d6d6e3798dbc43c63</citedby><cites>FETCH-LOGICAL-c549t-6f26c9aa1393add365d47c5d678226c9ef2933a16951d9a7d6d6e3798dbc43c63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0954611120303450$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33217538$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hussein, Mohammad H.</creatorcontrib><creatorcontrib>Toraih, Eman A.</creatorcontrib><creatorcontrib>Attia, Abdallah S.</creatorcontrib><creatorcontrib>Burley, Nicholas</creatorcontrib><creatorcontrib>Zhang, Allen D.</creatorcontrib><creatorcontrib>Roos, Jackson</creatorcontrib><creatorcontrib>Houghton, August</creatorcontrib><creatorcontrib>Aniemeka, Nedum</creatorcontrib><creatorcontrib>Omar, Mahmoud</creatorcontrib><creatorcontrib>Aboueisha, Mohamed</creatorcontrib><creatorcontrib>Shama, Mohamed A.</creatorcontrib><creatorcontrib>Duchesne, Juan</creatorcontrib><creatorcontrib>Kandil, Emad</creatorcontrib><title>Asthma in COVID-19 patients: An extra chain fitting around the neck?</title><title>Respiratory medicine</title><addtitle>Respir Med</addtitle><description>The novel coronavirus disease 2019 (COVID-19) has rapidly spread across the globe. Pre-existing comorbidities have been found to have a dramatic effect on the disease course. We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients.
We conducted a multi-center retrospective study of positively confirmed COVID-19 patients. The primary outcome of interest was in-hospital mortality. Secondary outcomes were the Intensive Care Unit (ICU) admission, intubation, mechanical ventilation, and length of hospital stay.
A total of 502 COVID-19 adult patients (72 asthma and 430 non-asthma cohorts) with mean age of 60.7 years were included in the study. The frequency of asthma in hospitalized cohorts was 14.3%. Univariate analysis revealed that asthma patients were more likely to be obese (75% versus 54.2%, p = 0.001), with a higher frequency of intubation (40.3% versus 27.8%, p = 0.036), and required a longer duration of hospitalization (15.1 ± 12.5 versus 11.5 ± 10.6, p = 0.015). After adjustment, multivariable analysis showed that asthmatic patients were not associated with higher risk of ICU admission (OR = 1.81, 95%CI = 0.98–3.09, p = 0.06), endotracheal intubation (OR = 1.77, 95%CI = 0.99–3.04, p = 0.06) or complications (OR = 1.37, 95%CI = 0.82–2.31, p = 0.23). Asthmatic patients were not associated with higher odds of prolonged hospital length of stay (OR = 1.48, 95%CI = 0.82–2.66, p = 0.20) or with ICU stay (OR = 0.76, 95%CI = 0.28–2.02, p = 0.58). Kaplan-Meier curve showed no significant difference in the overall survival of the two groups (p = 0.65).
Despite the increased prevalence of hospitalization in elder asthmatic COVID-19 patients, after adjustment for other variables, it was neither associated with increased severity nor worse outcomes.
[Display omitted]
•Asthma is more prevalent in COVID-19 cohort than in the general population.•Asthma was neither associated with disease severity nor negative outcomes.•Asthma does not imply a worse outcome as compared to non-asthmatics.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Asthma</subject><subject>Asthma - complications</subject><subject>Asthma - epidemiology</subject><subject>Case-Control Studies</subject><subject>Chronic lung disease</subject><subject>Comorbidity</subject><subject>Complications</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - complications</subject><subject>COVID-19 - diagnosis</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - virology</subject><subject>Disease Progression</subject><subject>Hospital Mortality - trends</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Intensive Care Units - statistics & numerical data</subject><subject>Intubation</subject><subject>Intubation, Intratracheal - statistics & numerical data</subject><subject>Length of Stay - statistics & numerical data</subject><subject>Mechanical ventilation</subject><subject>Medical prognosis</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Prevalence</subject><subject>Prognosis</subject><subject>Respiration, Artificial - statistics & numerical data</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2</subject><subject>SARS-CoV-2 - genetics</subject><subject>Ventilation</subject><issn>0954-6111</issn><issn>1532-3064</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1rGzEQhkVpSZykf6CHIugll3X0vVYpCcb5qMHgS9urkCVtLNfWOpI2JP8-WuyYtIecBJpnXmbmAeALRkOMsLhYDePG2SFBpP8QBPEPYIA5JRVFgn0EAyQ5qwTG-BicpLRCCEnG0BE4ppTgmtPRAFyPU15uNPQBTuZ_ptcVlnCrs3chp-9wHKB7ylFDs9SFaHzOPtxDHdsuWJiXDgZn_l6dgU-NXif3ef-egt-3N78mP6vZ_G46Gc8qw5nMlWiIMFJrTCXV1lLBLasNt6Iekb7iGiIp1VhIjq3UtRVWOFrLkV0YRo2gp-Byl7vtFmVzU4aMeq220W90fFat9urfSvBLdd8-qlrwutyhBJzvA2L70LmU1cYn49ZrHVzbJUWYoBiNJEYF_fYfumq7GMp6PcW4lETIQpEdZWKbUnTNYRiMVC9JrVQvSfWS1E5Safr6do1Dy6uVAvzYAa4c89G7qJIpRoyzPjqTlW39e_kvs8KgxQ</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Hussein, Mohammad H.</creator><creator>Toraih, Eman A.</creator><creator>Attia, Abdallah S.</creator><creator>Burley, Nicholas</creator><creator>Zhang, Allen D.</creator><creator>Roos, Jackson</creator><creator>Houghton, August</creator><creator>Aniemeka, Nedum</creator><creator>Omar, Mahmoud</creator><creator>Aboueisha, Mohamed</creator><creator>Shama, Mohamed A.</creator><creator>Duchesne, Juan</creator><creator>Kandil, Emad</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>ASE</scope><scope>FPQ</scope><scope>H94</scope><scope>K6X</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20201201</creationdate><title>Asthma in COVID-19 patients: An extra chain fitting around the neck?</title><author>Hussein, Mohammad H. ; Toraih, Eman A. ; Attia, Abdallah S. ; Burley, Nicholas ; Zhang, Allen D. ; Roos, Jackson ; Houghton, August ; Aniemeka, Nedum ; Omar, Mahmoud ; Aboueisha, Mohamed ; Shama, Mohamed A. ; Duchesne, Juan ; Kandil, Emad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c549t-6f26c9aa1393add365d47c5d678226c9ef2933a16951d9a7d6d6e3798dbc43c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Asthma</topic><topic>Asthma - complications</topic><topic>Asthma - epidemiology</topic><topic>Case-Control Studies</topic><topic>Chronic lung disease</topic><topic>Comorbidity</topic><topic>Complications</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 - complications</topic><topic>COVID-19 - diagnosis</topic><topic>COVID-19 - epidemiology</topic><topic>COVID-19 - virology</topic><topic>Disease Progression</topic><topic>Hospital Mortality - trends</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Intensive Care Units - statistics & numerical data</topic><topic>Intubation</topic><topic>Intubation, Intratracheal - statistics & numerical data</topic><topic>Length of Stay - statistics & numerical data</topic><topic>Mechanical ventilation</topic><topic>Medical prognosis</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Prevalence</topic><topic>Prognosis</topic><topic>Respiration, Artificial - statistics & numerical data</topic><topic>Retrospective Studies</topic><topic>SARS-CoV-2</topic><topic>SARS-CoV-2 - genetics</topic><topic>Ventilation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hussein, Mohammad H.</creatorcontrib><creatorcontrib>Toraih, Eman A.</creatorcontrib><creatorcontrib>Attia, Abdallah S.</creatorcontrib><creatorcontrib>Burley, Nicholas</creatorcontrib><creatorcontrib>Zhang, Allen D.</creatorcontrib><creatorcontrib>Roos, Jackson</creatorcontrib><creatorcontrib>Houghton, August</creatorcontrib><creatorcontrib>Aniemeka, Nedum</creatorcontrib><creatorcontrib>Omar, Mahmoud</creatorcontrib><creatorcontrib>Aboueisha, Mohamed</creatorcontrib><creatorcontrib>Shama, Mohamed A.</creatorcontrib><creatorcontrib>Duchesne, Juan</creatorcontrib><creatorcontrib>Kandil, Emad</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Respiratory medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hussein, Mohammad H.</au><au>Toraih, Eman A.</au><au>Attia, Abdallah S.</au><au>Burley, Nicholas</au><au>Zhang, Allen D.</au><au>Roos, Jackson</au><au>Houghton, August</au><au>Aniemeka, Nedum</au><au>Omar, Mahmoud</au><au>Aboueisha, Mohamed</au><au>Shama, Mohamed A.</au><au>Duchesne, Juan</au><au>Kandil, Emad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Asthma in COVID-19 patients: An extra chain fitting around the neck?</atitle><jtitle>Respiratory medicine</jtitle><addtitle>Respir Med</addtitle><date>2020-12-01</date><risdate>2020</risdate><volume>175</volume><spage>106205</spage><epage>106205</epage><pages>106205-106205</pages><artnum>106205</artnum><issn>0954-6111</issn><eissn>1532-3064</eissn><abstract>The novel coronavirus disease 2019 (COVID-19) has rapidly spread across the globe. Pre-existing comorbidities have been found to have a dramatic effect on the disease course. We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients.
We conducted a multi-center retrospective study of positively confirmed COVID-19 patients. The primary outcome of interest was in-hospital mortality. Secondary outcomes were the Intensive Care Unit (ICU) admission, intubation, mechanical ventilation, and length of hospital stay.
A total of 502 COVID-19 adult patients (72 asthma and 430 non-asthma cohorts) with mean age of 60.7 years were included in the study. The frequency of asthma in hospitalized cohorts was 14.3%. Univariate analysis revealed that asthma patients were more likely to be obese (75% versus 54.2%, p = 0.001), with a higher frequency of intubation (40.3% versus 27.8%, p = 0.036), and required a longer duration of hospitalization (15.1 ± 12.5 versus 11.5 ± 10.6, p = 0.015). After adjustment, multivariable analysis showed that asthmatic patients were not associated with higher risk of ICU admission (OR = 1.81, 95%CI = 0.98–3.09, p = 0.06), endotracheal intubation (OR = 1.77, 95%CI = 0.99–3.04, p = 0.06) or complications (OR = 1.37, 95%CI = 0.82–2.31, p = 0.23). Asthmatic patients were not associated with higher odds of prolonged hospital length of stay (OR = 1.48, 95%CI = 0.82–2.66, p = 0.20) or with ICU stay (OR = 0.76, 95%CI = 0.28–2.02, p = 0.58). Kaplan-Meier curve showed no significant difference in the overall survival of the two groups (p = 0.65).
Despite the increased prevalence of hospitalization in elder asthmatic COVID-19 patients, after adjustment for other variables, it was neither associated with increased severity nor worse outcomes.
[Display omitted]
•Asthma is more prevalent in COVID-19 cohort than in the general population.•Asthma was neither associated with disease severity nor negative outcomes.•Asthma does not imply a worse outcome as compared to non-asthmatics.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>33217538</pmid><doi>10.1016/j.rmed.2020.106205</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Aged, 80 and over Asthma Asthma - complications Asthma - epidemiology Case-Control Studies Chronic lung disease Comorbidity Complications Coronaviruses COVID-19 COVID-19 - complications COVID-19 - diagnosis COVID-19 - epidemiology COVID-19 - virology Disease Progression Hospital Mortality - trends Hospitalization - statistics & numerical data Humans Intensive Care Units - statistics & numerical data Intubation Intubation, Intratracheal - statistics & numerical data Length of Stay - statistics & numerical data Mechanical ventilation Medical prognosis Middle Aged Obesity Prevalence Prognosis Respiration, Artificial - statistics & numerical data Retrospective Studies SARS-CoV-2 SARS-CoV-2 - genetics Ventilation |
| title | Asthma in COVID-19 patients: An extra chain fitting around the neck? |
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