Independent Prognostic Potential of GNPNAT1 in Lung Adenocarcinoma

Background. Glucosamine-Phosphate N-Acetyltransferase 1 (GNPNAT1) is a critical enzyme in the biosynthesis of uridine diphosphate-N-acetylglucosamine. It has many important functions, such as protein binding, monosaccharide binding, and embryonic development and growth. However, the role of GNPNAT1...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-16
Hauptverfasser:	Luo, Huan, Zhang, Yanmin, Zhang, Jinjun, Ma, Chao, Li, Yongwei, Zheng, Xiangyu, Fu, Zongqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyltransferase Adenocarcinoma Adenocarcinoma of Lung - enzymology Adenocarcinoma of Lung - genetics Adenocarcinoma of Lung - immunology Aged Analysis B-Lymphocytes - immunology Binding Biomarkers, Tumor - genetics Biosynthesis Care and treatment CD4 antigen Cell cycle Cohort Studies Correlation analysis Datasets Dendritic cells Diagnosis E2F protein Embryogenesis Embryonic growth stage Epidermal growth factor receptors Female Gene expression Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Gene mutations Gene Regulatory Networks Glucosamine Glucosamine 6-Phosphate N-Acetyltransferase - metabolism Health aspects Humans Immune response Immune system Immunomodulation Kaplan-Meier Estimate Kinases Lung cancer Lung Neoplasms - enzymology Lung Neoplasms - genetics Lung Neoplasms - immunology Lungs Lymphocytes Lymphocytes B Lymphocytes T Male Medical prognosis Metastases Middle Aged Monosaccharides Multivariate Analysis Mutation Mutation - genetics N-Acetylglucosamine N-acetyltransferase 1 Neoplasm Proteins - genetics Network analysis p53 Protein Prognosis Proteasomes Protein binding Risk analysis Risk Factors RNA transport Signatures Survival Analysis Tumor-infiltrating lymphocytes Tumors Uridine
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