Cell culture system to assay candidate genes and molecular pathways implicated in congenital diaphragmatic hernias

The mammalian muscularized diaphragm is essential for respiration and defects in the developing diaphragm cause a common and frequently lethal birth defect, congenital diaphragmatic hernia (CDH). Human genetic studies have implicated more than 150 genes and multiple molecular pathways in CDH, but fe...

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Veröffentlicht in:	Developmental biology 2020-11, Vol.467 (1-2), p.30-38
Hauptverfasser:	Bogenschutz, Eric L., Sefton, Elizabeth M., Kardon, Gabrielle
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CDH Cell culture Cell Culture Techniques Congenital diaphragmatic hernia Diaphragm Diaphragm - embryology Female Fibroblasts Gene Expression Regulation, Developmental Hernias, Diaphragmatic, Congenital - embryology Humans Male Mice NIH 3T3 Cells
Online-Zugang:	Volltext
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