Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages

The cellular complexity and scale of the early liver have constrained analyses examining its emergence during organogenesis. To circumvent these issues, we analyzed 45,334 single-cell transcriptomes from embryonic day (E)7.5, when endoderm progenitors are specified, to E10.5 liver, when liver parenc...

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Veröffentlicht in:	Cell 2020-10, Vol.183 (3), p.702-716.e14
Hauptverfasser:	Lotto, Jeremy, Drissler, Sibyl, Cullum, Rebecca, Wei, Wei, Setty, Manu, Bell, Erin M., Boutet, Stéphane C., Nowotschin, Sonja, Kuo, Ying-Yi, Garg, Vidur, Pe’er, Dana, Church, Deanna M., Hadjantonakis, Anna-Katerina, Hoodless, Pamela A.
Format:	Artikel
Sprache:	eng
Schlagworte:	endoderm hepatoblasts liver mesothelium organogenesis scRNA-seq single-cell sinusoidal endothelium stellate cells
Online-Zugang:	Volltext
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