Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study

Invasive pneumococcal disease remains an important health priority owing to increasing disease incidence caused by pneumococci expressing non-vaccine serotypes. We previously defined 621 Global Pneumococcal Sequence Clusters (GPSCs) by analysing 20 027 pneumococcal isolates collected worldwide and f...

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Veröffentlicht in:	The Lancet infectious diseases 2019-07, Vol.19 (7), p.759-769
Hauptverfasser:	Lo, Stephanie W, Gladstone, Rebecca A, van Tonder, Andries J, Lees, John A, du Plessis, Mignon, Benisty, Rachel, Givon-Lavi, Noga, Hawkins, Paulina A, Cornick, Jennifer E, Kwambana-Adams, Brenda, Law, Pierra Y, Ho, Pak Leung, Antonio, Martin, Everett, Dean B, Dagan, Ron, von Gottberg, Anne, Klugman, Keith P, McGee, Lesley, Breiman, Robert F, Bentley, Stephen D, Brooks, Abdullah W, Corso, Alejandra, Davydov, Alexander, Maguire, Alison, Pollard, Andrew, Kiran, Anmol, Skoczynska, Anna, Moiane, Benild, Beall, Bernard, Sigauque, Betuel, Aanensen, David, Lehmann, Deborah, Faccone, Diego, Foster-Nyarko, Ebenezer, Bojang, Ebrima, Egorova, Ekaterina, Voropaeva, Elena, Sampane-Donkor, Eric, Sadowy, Ewa, Bigogo, Godfrey, Mucavele, Helio, Belabbès, Houria, Diawara, Idrissa, Moïsi, Jennifer, Verani, Jennifer, Keenan, Jeremy, Nair Thulasee Bhai, Jyothish N, Ndlangisa, Kedibone M, Zerouali, Khalid, Ravikumar, K L, Titov, Leonid, De Gouveia, Linda, Alaerts, Maaike, Ip, Margaret, de Cunto Brandileone, Maria Cristina, Hasanuzzaman, Md, Paragi, Metka, Nurse-Lucas, Michele, Ali, Mushal, Elmdaghri, Naima, Croucher, Nicholas, Wolter, Nicole, Porat, Nurit, Eser, Özgen Köseoglu, Akpaka, Patrick E, Turner, Paul, Gagetti, Paula, Tientcheu, Peggy-Estelle, Carter, Philip E, Mostowy, Rafal, Kandasamy, Rama, Ford, Rebecca, Henderson, Rebecca, Malaker, Roly, Shakoor, Sadia, Grassi Almeida, Samanta Cristine, Saha, Samir K, Doiphode, Sanjay, Madhi, Shabir A, Devi Sekaran, Shamala, Srifuengfung, Somporn, Obaro, Stephen, Clarke, Stuart C, Nzenze, Susan A, Kastrin, Tamara, Ochoa, Theresa J, Balaji, Veeraraghavan, Hryniewicz, Waleria, Urban, Yulia
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa - epidemiology Antibiotic resistance Antibiotics Charities Child, Preschool Childhood Children Cloning Cluster analysis Design optimization Disease Disease control Disease prevention Drug resistance Drug Resistance, Microbial Erythromycin Female Gene sequencing Genomes Hong Kong - epidemiology Humans Immunization Incidence Infant Infant, Newborn Infectious diseases Israel - epidemiology Male Penicillin Pneumococcal Infections - epidemiology Pneumococcal Infections - prevention & control Pneumococcal Vaccines - administration & dosage Pneumococcal Vaccines - immunology Population Prevalence Serogroup Serotypes Spreading Streptococcus pneumoniae - immunology Studies Surveillance Vaccines Vaccines, Conjugate Whole Genome Sequencing
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