Evaluation of Left Ventricular Myocardial Work Performance in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery
Purpose: Benefits of off-pump coronary bypass (OPCAB) over on-pump (ONCAB) remain controversial. We aimed to evaluate the early impacts of OPCAB vs ONCAB for varying left ventricular (LV) function baselines by applying the non-invasive myocardial work (MW) analysis, which enables further insights in...
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| Veröffentlicht in: | Annals of Thoracic and Cardiovascular Surgery 2020, Vol.26(5), pp.276-285 |
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| creator | Spetsotaki, Konstantina Zayat, Rashad Donuru, Srinath Autschbach, Ruediger Schnoering, Heike Hatam, Nima |
| description | Purpose: Benefits of off-pump coronary bypass (OPCAB) over on-pump (ONCAB) remain controversial. We aimed to evaluate the early impacts of OPCAB vs ONCAB for varying left ventricular (LV) function baselines by applying the non-invasive myocardial work (MW) analysis, which enables further insights in cardiac mechanics, contractility, and efficacy.Methods: We retrospectively analyzed 98 patients (55 ONCAB vs 43 OPCAB). Transthoracic echocardiography (TTE) and concurrent arterial blood pressure measurements taken at rest, prior to, and early after surgery were performed. Global myocardial work index (GMWI), global constructive work (GCW), and global work efficiency (GWE), inter alia, were quantified.Results: Preoperatively, OPCAB patients had significantly lower values than ONCAB patients in terms of GMWI (1404.33 ± 585.41 mmHg% vs 1619.07 ± 535.42 mmHg%, p = 0.039), GWE (90% (60%, 96%) vs 93% (74%, 98%), p = 0.028). After surgery, GMWI was reduced in both groups. However, a more significant GMWI impairment occurred early after ONCAB than after OPCAB (−343.14 ± 35.20 mmHg%, p |
| doi_str_mv | 10.5761/atcs.oa.20-00066 |
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| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7641886</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2440666040</sourcerecordid><originalsourceid>FETCH-LOGICAL-c650t-5b1bc65dd39ea7fe7f02549745106e0fc58a15a04ebd80f7f40ff96d395be9953</originalsourceid><addsrcrecordid>eNpVkcFu1DAQhi0Eokvhzgn5yCXLOImd5IJUVi1FWrQrQeFoTRw7dcnai51U2gfgveslZVUunhn5m39m9BPylsGSV4J9wFHFpcdlDhkACPGMLHJWi4wB8OdkwYqSpbypz8irGO8AiloIeEnOirxuijwvF-TP5T0OE47WO-oNXWsz0h_ajcGqacBAvx68wtBZHOhPH37RrQ7Ghx06pal1dJs6Ex3pjet06L11Pd24bDvt9hRdRzfGzMXKB-8wHOhFGHUKnw57jJF-m0KfytfkhcEh6jeP8ZzcXF1-X11n683nL6uLdaYEhzHjLWtT1nVFo7EyujKQ87KpSs5AaDCK18g4QqnbrgZTmRKMaUTCeaubhhfn5OOsu5_ane7U8VAc5D7YXdpNerTy_x9nb2Xv72UlSlbXIgm8fxQI_vek4yh3Nio9DOi0n6LMyzLZIKCEhMKMquBjDNqcxjCQR_fk0b00U-Yg_7qXWt49Xe_U8M-uBFzNwF0csdcnAMNo1aBnxVxIfnyeKJ8AdYtBalc8AKSgs-o</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2440666040</pqid></control><display><type>article</type><title>Evaluation of Left Ventricular Myocardial Work Performance in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery</title><source>J-STAGE Free</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Spetsotaki, Konstantina ; Zayat, Rashad ; Donuru, Srinath ; Autschbach, Ruediger ; Schnoering, Heike ; Hatam, Nima</creator><creatorcontrib>Spetsotaki, Konstantina ; Zayat, Rashad ; Donuru, Srinath ; Autschbach, Ruediger ; Schnoering, Heike ; Hatam, Nima</creatorcontrib><description>Purpose: Benefits of off-pump coronary bypass (OPCAB) over on-pump (ONCAB) remain controversial. We aimed to evaluate the early impacts of OPCAB vs ONCAB for varying left ventricular (LV) function baselines by applying the non-invasive myocardial work (MW) analysis, which enables further insights in cardiac mechanics, contractility, and efficacy.Methods: We retrospectively analyzed 98 patients (55 ONCAB vs 43 OPCAB). Transthoracic echocardiography (TTE) and concurrent arterial blood pressure measurements taken at rest, prior to, and early after surgery were performed. Global myocardial work index (GMWI), global constructive work (GCW), and global work efficiency (GWE), inter alia, were quantified.Results: Preoperatively, OPCAB patients had significantly lower values than ONCAB patients in terms of GMWI (1404.33 ± 585.41 mmHg% vs 1619.07 ± 535.42 mmHg%, p = 0.039), GWE (90% (60%, 96%) vs 93% (74%, 98%), p = 0.028). After surgery, GMWI was reduced in both groups. However, a more significant GMWI impairment occurred early after ONCAB than after OPCAB (−343.14 ± 35.20 mmHg%, p <0.001 vs −224.04 ± 120.91 mmHg%, p = 0.042).Conclusion: Despite lower preoperative LV function in OPCAB patients, GMWIs after OPCAB were superior to ONCAB, indicating better preservation of systolic LV function early after OPCAB by means of contractility compared to ONCAB. Further studies should investigate the long-term course of MW response and their clinical impact.</description><identifier>ISSN: 1341-1098</identifier><identifier>EISSN: 2186-1005</identifier><identifier>DOI: 10.5761/atcs.oa.20-00066</identifier><identifier>PMID: 32893224</identifier><language>eng</language><publisher>Japan: The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery</publisher><subject>Aged ; Cardiopulmonary Bypass - adverse effects ; Coronary Artery Bypass - adverse effects ; Coronary Artery Bypass, Off-Pump - adverse effects ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - physiopathology ; Coronary Artery Disease - surgery ; echocardiography ; Female ; global myocardial work ; Humans ; left ventricular systolic function ; Male ; Middle Aged ; Myocardial Contraction ; non-invasive ; off-pump coronary surgery ; Original ; Retrospective Studies ; Treatment Outcome ; Ventricular Dysfunction, Left - etiology ; Ventricular Dysfunction, Left - physiopathology ; Ventricular Function, Left</subject><ispartof>Annals of Thoracic and Cardiovascular Surgery, 2020, Vol.26(5), pp.276-285</ispartof><rights>2020 The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery</rights><rights>2020 Annals of Thoracic and Cardiovascular Surgery 2020</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c650t-5b1bc65dd39ea7fe7f02549745106e0fc58a15a04ebd80f7f40ff96d395be9953</citedby><cites>FETCH-LOGICAL-c650t-5b1bc65dd39ea7fe7f02549745106e0fc58a15a04ebd80f7f40ff96d395be9953</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641886/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641886/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1877,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32893224$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spetsotaki, Konstantina</creatorcontrib><creatorcontrib>Zayat, Rashad</creatorcontrib><creatorcontrib>Donuru, Srinath</creatorcontrib><creatorcontrib>Autschbach, Ruediger</creatorcontrib><creatorcontrib>Schnoering, Heike</creatorcontrib><creatorcontrib>Hatam, Nima</creatorcontrib><title>Evaluation of Left Ventricular Myocardial Work Performance in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery</title><title>Annals of Thoracic and Cardiovascular Surgery</title><addtitle>ATCS</addtitle><description>Purpose: Benefits of off-pump coronary bypass (OPCAB) over on-pump (ONCAB) remain controversial. We aimed to evaluate the early impacts of OPCAB vs ONCAB for varying left ventricular (LV) function baselines by applying the non-invasive myocardial work (MW) analysis, which enables further insights in cardiac mechanics, contractility, and efficacy.Methods: We retrospectively analyzed 98 patients (55 ONCAB vs 43 OPCAB). Transthoracic echocardiography (TTE) and concurrent arterial blood pressure measurements taken at rest, prior to, and early after surgery were performed. Global myocardial work index (GMWI), global constructive work (GCW), and global work efficiency (GWE), inter alia, were quantified.Results: Preoperatively, OPCAB patients had significantly lower values than ONCAB patients in terms of GMWI (1404.33 ± 585.41 mmHg% vs 1619.07 ± 535.42 mmHg%, p = 0.039), GWE (90% (60%, 96%) vs 93% (74%, 98%), p = 0.028). After surgery, GMWI was reduced in both groups. However, a more significant GMWI impairment occurred early after ONCAB than after OPCAB (−343.14 ± 35.20 mmHg%, p <0.001 vs −224.04 ± 120.91 mmHg%, p = 0.042).Conclusion: Despite lower preoperative LV function in OPCAB patients, GMWIs after OPCAB were superior to ONCAB, indicating better preservation of systolic LV function early after OPCAB by means of contractility compared to ONCAB. Further studies should investigate the long-term course of MW response and their clinical impact.</description><subject>Aged</subject><subject>Cardiopulmonary Bypass - adverse effects</subject><subject>Coronary Artery Bypass - adverse effects</subject><subject>Coronary Artery Bypass, Off-Pump - adverse effects</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - physiopathology</subject><subject>Coronary Artery Disease - surgery</subject><subject>echocardiography</subject><subject>Female</subject><subject>global myocardial work</subject><subject>Humans</subject><subject>left ventricular systolic function</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Contraction</subject><subject>non-invasive</subject><subject>off-pump coronary surgery</subject><subject>Original</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Ventricular Dysfunction, Left - etiology</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><subject>Ventricular Function, Left</subject><issn>1341-1098</issn><issn>2186-1005</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkcFu1DAQhi0Eokvhzgn5yCXLOImd5IJUVi1FWrQrQeFoTRw7dcnai51U2gfgveslZVUunhn5m39m9BPylsGSV4J9wFHFpcdlDhkACPGMLHJWi4wB8OdkwYqSpbypz8irGO8AiloIeEnOirxuijwvF-TP5T0OE47WO-oNXWsz0h_ajcGqacBAvx68wtBZHOhPH37RrQ7Ghx06pal1dJs6Ex3pjet06L11Pd24bDvt9hRdRzfGzMXKB-8wHOhFGHUKnw57jJF-m0KfytfkhcEh6jeP8ZzcXF1-X11n683nL6uLdaYEhzHjLWtT1nVFo7EyujKQ87KpSs5AaDCK18g4QqnbrgZTmRKMaUTCeaubhhfn5OOsu5_ane7U8VAc5D7YXdpNerTy_x9nb2Xv72UlSlbXIgm8fxQI_vek4yh3Nio9DOi0n6LMyzLZIKCEhMKMquBjDNqcxjCQR_fk0b00U-Yg_7qXWt49Xe_U8M-uBFzNwF0csdcnAMNo1aBnxVxIfnyeKJ8AdYtBalc8AKSgs-o</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Spetsotaki, Konstantina</creator><creator>Zayat, Rashad</creator><creator>Donuru, Srinath</creator><creator>Autschbach, Ruediger</creator><creator>Schnoering, Heike</creator><creator>Hatam, Nima</creator><general>The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200101</creationdate><title>Evaluation of Left Ventricular Myocardial Work Performance in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery</title><author>Spetsotaki, Konstantina ; Zayat, Rashad ; Donuru, Srinath ; Autschbach, Ruediger ; Schnoering, Heike ; Hatam, Nima</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c650t-5b1bc65dd39ea7fe7f02549745106e0fc58a15a04ebd80f7f40ff96d395be9953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Cardiopulmonary Bypass - adverse effects</topic><topic>Coronary Artery Bypass - adverse effects</topic><topic>Coronary Artery Bypass, Off-Pump - adverse effects</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - physiopathology</topic><topic>Coronary Artery Disease - surgery</topic><topic>echocardiography</topic><topic>Female</topic><topic>global myocardial work</topic><topic>Humans</topic><topic>left ventricular systolic function</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Contraction</topic><topic>non-invasive</topic><topic>off-pump coronary surgery</topic><topic>Original</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Ventricular Dysfunction, Left - etiology</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><topic>Ventricular Function, Left</topic><toplevel>online_resources</toplevel><creatorcontrib>Spetsotaki, Konstantina</creatorcontrib><creatorcontrib>Zayat, Rashad</creatorcontrib><creatorcontrib>Donuru, Srinath</creatorcontrib><creatorcontrib>Autschbach, Ruediger</creatorcontrib><creatorcontrib>Schnoering, Heike</creatorcontrib><creatorcontrib>Hatam, Nima</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of Thoracic and Cardiovascular Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spetsotaki, Konstantina</au><au>Zayat, Rashad</au><au>Donuru, Srinath</au><au>Autschbach, Ruediger</au><au>Schnoering, Heike</au><au>Hatam, Nima</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Left Ventricular Myocardial Work Performance in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery</atitle><jtitle>Annals of Thoracic and Cardiovascular Surgery</jtitle><addtitle>ATCS</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>26</volume><issue>5</issue><spage>276</spage><epage>285</epage><pages>276-285</pages><issn>1341-1098</issn><eissn>2186-1005</eissn><abstract>Purpose: Benefits of off-pump coronary bypass (OPCAB) over on-pump (ONCAB) remain controversial. We aimed to evaluate the early impacts of OPCAB vs ONCAB for varying left ventricular (LV) function baselines by applying the non-invasive myocardial work (MW) analysis, which enables further insights in cardiac mechanics, contractility, and efficacy.Methods: We retrospectively analyzed 98 patients (55 ONCAB vs 43 OPCAB). Transthoracic echocardiography (TTE) and concurrent arterial blood pressure measurements taken at rest, prior to, and early after surgery were performed. Global myocardial work index (GMWI), global constructive work (GCW), and global work efficiency (GWE), inter alia, were quantified.Results: Preoperatively, OPCAB patients had significantly lower values than ONCAB patients in terms of GMWI (1404.33 ± 585.41 mmHg% vs 1619.07 ± 535.42 mmHg%, p = 0.039), GWE (90% (60%, 96%) vs 93% (74%, 98%), p = 0.028). After surgery, GMWI was reduced in both groups. However, a more significant GMWI impairment occurred early after ONCAB than after OPCAB (−343.14 ± 35.20 mmHg%, p <0.001 vs −224.04 ± 120.91 mmHg%, p = 0.042).Conclusion: Despite lower preoperative LV function in OPCAB patients, GMWIs after OPCAB were superior to ONCAB, indicating better preservation of systolic LV function early after OPCAB by means of contractility compared to ONCAB. Further studies should investigate the long-term course of MW response and their clinical impact.</abstract><cop>Japan</cop><pub>The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery</pub><pmid>32893224</pmid><doi>10.5761/atcs.oa.20-00066</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aged Cardiopulmonary Bypass - adverse effects Coronary Artery Bypass - adverse effects Coronary Artery Bypass, Off-Pump - adverse effects Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Coronary Artery Disease - surgery echocardiography Female global myocardial work Humans left ventricular systolic function Male Middle Aged Myocardial Contraction non-invasive off-pump coronary surgery Original Retrospective Studies Treatment Outcome Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - physiopathology Ventricular Function, Left |
| title | Evaluation of Left Ventricular Myocardial Work Performance in Patients Undergoing On-Pump and Off-Pump Coronary Artery Bypass Surgery |
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