ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B–H4K8ac–BRD4 axis

Abstract Centromeres are genomic regions essential for faithful chromosome segregation. Transcription of noncoding RNA (ncRNA) at centromeres is important for their formation and functions. Here, we report the molecular mechanism by which the transcriptional regulator ZFAT controls the centromeric n...

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Veröffentlicht in:	Nucleic acids research 2020-11, Vol.48 (19), p.10848-10866
Hauptverfasser:	Ishikura, Shuhei, Nakabayashi, Kazuhiko, Nagai, Masayoshi, Tsunoda, Toshiyuki, Shirasawa, Senji
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene regulation, Chromatin and Epigenetics
Online-Zugang:	Volltext
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