RaptRanker: in silico RNA aptamer selection from HT-SELEX experiment based on local sequence and structure information

Abstract Aptamers are short single-stranded RNA/DNA molecules that bind to specific target molecules. Aptamers with high binding-affinity and target specificity are identified using an in vitro procedure called high throughput systematic evolution of ligands by exponential enrichment (HT-SELEX). How...

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Veröffentlicht in:	Nucleic acids research 2020-08, Vol.48 (14), p.e82-e82
Hauptverfasser:	Ishida, Ryoga, Adachi, Tatsuo, Yokota, Aya, Yoshihara, Hidehito, Aoki, Kazuteru, Nakamura, Yoshikazu, Hamada, Michiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Biology and Nucleic Acid Chemistry
Online-Zugang:	Volltext
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