The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils

Neutrophils are critical to the generation of effective immune responses and for killing invading microbes. Paired immune receptors provide important mechanisms to modulate neutrophil activation thresholds and effector functions. Expression of the leukocyte Ig-like receptor (LILR)A6 (ILT8/CD85b) and...

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Veröffentlicht in:	The Journal of immunology (1950) 2020-02, Vol.204 (4), p.954-966
Hauptverfasser:	Zhao, Yuxi, van Woudenbergh, Esther, Zhu, Jing, Heck, Albert J R, van Kessel, Kok P M, de Haas, Carla J C, Aerts, Piet C, van Strijp, Jos A G, McCarthy, Alex J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - genetics Antigens, CD - isolation & purification Antigens, CD - metabolism Cell Differentiation - immunology Cell Line Down-Regulation - immunology Humans Neutrophil Activation Neutrophils - immunology Neutrophils - metabolism Phagocytosis Primary Cell Culture Reactive Oxygen Species - metabolism Receptors, Fc - metabolism Receptors, Immunologic - genetics Receptors, Immunologic - isolation & purification Receptors, Immunologic - metabolism Recombinant Proteins - genetics Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism Staphylococcal Infections - immunology Staphylococcal Infections - microbiology Staphylococcus capitis - immunology
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