Sister chromatid cohesion establishment during DNA replication termination

Newly copied sister chromatids are tethered together by the cohesin complex, but how sister chromatid cohesion coordinates with DNA replication is poorly understood. Prevailing models suggest that cohesin complexes, bound to DNA before replication, remain behind the advancing replication fork to kee...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2024-04, Vol.384 (6691), p.119-124
Hauptverfasser:	Cameron, George, Gruszka, Dominika T, Gruar, Rhian, Xie, Sherry, Kaya, Çağla, Nasmyth, Kim A, Baxter, Jonathan, Srinivasan, Madhusudhan, Yardimci, Hasan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell division Chromatids - metabolism Chromosomal Proteins, Non-Histone - metabolism Chromosomes Cohesin Cohesins - metabolism Cohesion Convergence Deoxyribonucleic acid Dismantling DNA DNA biosynthesis DNA Replication DNA-Binding Proteins - metabolism Minichromosome Maintenance Proteins - metabolism Nuclear Proteins - metabolism Replication Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Sister Chromatid Exchange
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