Cellular senescence is immunogenic and promotes anti-tumor immunity

Cellular senescence is a stress response that activates innate immune cells, but little is known about its interplay with the adaptive immune system. Here, we show that senescent cells combine several features that render them highly efficient in activating dendritic cells (DCs) and antigen-specific...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer discovery 2022-10, Vol.13 (2), p.410-431
Hauptverfasser:	Marin, Ines, Boix, Olga, Garcia-Garijo, Andrea, Sirois, Isabelle, Caballe, Adrià, Zarzuela, Eduardo, Ruano, Irene, Attolini, Camille Stephan-Otto, Prats, Neus, López-Domínguez, José A, Kovatcheva, Marta, Garralda, Elena, Muñoz, Javier, Caron, Etienne, Abad, María, Gros, Alena, Pietrocola, Federico, Serrano, Manuel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!