The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization

Macrophages polarize into functionally distinct subtypes while responding to microenvironmental cues. The identity of proximal transcription factors (TFs) downstream from the polarization signals are known, but their activity is typically transient, failing to explain the long-term, stable epigenomi...

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Veröffentlicht in:	Genes & development 2020-11, Vol.34 (21-22), p.1474-1492
Hauptverfasser:	Daniel, Bence, Czimmerer, Zsolt, Halasz, Laszlo, Boto, Pal, Kolostyak, Zsuzsanna, Poliska, Szilard, Berger, Wilhelm K, Tzerpos, Petros, Nagy, Gergely, Horvath, Attila, Hajas, György, Cseh, Timea, Nagy, Aniko, Sauer, Sascha, Francois-Deleuze, Jean, Szatmari, Istvan, Bacsi, Attila, Nagy, Laszlo
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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