Primary ectopic Merkel cell carcinoma without skin involvement—report of a case with prolonged survival

Abstract Merkel cell carcinoma is a rare neuroendocrine malignancy that arises from the dermis, in cases of immunocompromised, middle-aged patients or on skin exposed to sunlight. It only rarely presents in extra-cutaneous locations. We present the case of a 63-year-old female with a mass in the adi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of surgical case reports 2020-10, Vol.2020 (10)
Hauptverfasser: Effraimidou, Eleni, Kofina, Konstantinia, Giatromanolaki, Alexandra, Chatzipantelis, Paschalis, Karanikas, Michael, Lyratzopoulos, Nicolaos
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 10
container_start_page
container_title Journal of surgical case reports
container_volume 2020
creator Effraimidou, Eleni
Kofina, Konstantinia
Giatromanolaki, Alexandra
Chatzipantelis, Paschalis
Karanikas, Michael
Lyratzopoulos, Nicolaos
description Abstract Merkel cell carcinoma is a rare neuroendocrine malignancy that arises from the dermis, in cases of immunocompromised, middle-aged patients or on skin exposed to sunlight. It only rarely presents in extra-cutaneous locations. We present the case of a 63-year-old female with a mass in the adipose tissue of the upper arm, without skin involvement and concurrent axillary lymph node enlargement. She was treated with wide excision and lymph node dissection; pathology led to the diagnosis of Merkel cell carcinoma, and she was subsequently submitted to adjuvant radiotherapy. No signs of recurrence are present 8 years postoperatively. Primary Merkel cell carcinoma can rarely be located in the adipose tissue without skin involvement. In cases of high suspicion, preoperative MRI scan can show the extent of the lesion, as well as lymph metastases.
doi_str_mv 10.1093/jscr/rjaa390
format Article
fullrecord <record><control><sourceid>oup_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7605217</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/jscr/rjaa390</oup_id><sourcerecordid>10.1093/jscr/rjaa390</sourcerecordid><originalsourceid>FETCH-LOGICAL-c317t-4a17102e4f6c10a1ad4c478f30a724483682417d2be1315b519ad9207787fffb3</originalsourceid><addsrcrecordid>eNp9UMtOwzAQtBCIVqU3PsA3LoR6bTdOLkio4iUVwQHOkeM4rdskjuwkiBsfwRfyJaSkQnBhD7sr7cxoZxA6BXIBJGazjVdu5jZSspgcoDElnAZRBPTw1z5CU-83pC8eA0ThMRoxBiGDORsj8-RMKd0b1qqxtVH4QbutLrDSRd-kU6aypcSvplnbtsF-aypsqs4WnS511Xy-fzhdW9dgm2PZE7z-xuLa2cJWK51h37rOdLI4QUe5LLye7ucEvdxcPy_uguXj7f3iahkoBqIJuAQBhGqehwqIBJlxxUWUMyIF5TxiYUQ5iIymGnoL6RximcWUCBGJPM9TNkGXg27dpqXOVP-lk0VSDz4TK03y91KZdbKyXSJCMqcgeoHzQUA5673T-Q8XSLJLPdmlnuxT7-FnA9y29f_IL-DJhrM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Primary ectopic Merkel cell carcinoma without skin involvement—report of a case with prolonged survival</title><source>Oxford Journals Open Access Collection</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Effraimidou, Eleni ; Kofina, Konstantinia ; Giatromanolaki, Alexandra ; Chatzipantelis, Paschalis ; Karanikas, Michael ; Lyratzopoulos, Nicolaos</creator><creatorcontrib>Effraimidou, Eleni ; Kofina, Konstantinia ; Giatromanolaki, Alexandra ; Chatzipantelis, Paschalis ; Karanikas, Michael ; Lyratzopoulos, Nicolaos</creatorcontrib><description>Abstract Merkel cell carcinoma is a rare neuroendocrine malignancy that arises from the dermis, in cases of immunocompromised, middle-aged patients or on skin exposed to sunlight. It only rarely presents in extra-cutaneous locations. We present the case of a 63-year-old female with a mass in the adipose tissue of the upper arm, without skin involvement and concurrent axillary lymph node enlargement. She was treated with wide excision and lymph node dissection; pathology led to the diagnosis of Merkel cell carcinoma, and she was subsequently submitted to adjuvant radiotherapy. No signs of recurrence are present 8 years postoperatively. Primary Merkel cell carcinoma can rarely be located in the adipose tissue without skin involvement. In cases of high suspicion, preoperative MRI scan can show the extent of the lesion, as well as lymph metastases.</description><identifier>ISSN: 2042-8812</identifier><identifier>EISSN: 2042-8812</identifier><identifier>DOI: 10.1093/jscr/rjaa390</identifier><identifier>PMID: 33163153</identifier><language>eng</language><publisher>Oxford University Press</publisher><subject>Case Report</subject><ispartof>Journal of surgical case reports, 2020-10, Vol.2020 (10)</ispartof><rights>Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c317t-4a17102e4f6c10a1ad4c478f30a724483682417d2be1315b519ad9207787fffb3</cites><orcidid>0000-0002-8052-2807</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605217/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605217/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,1604,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>Effraimidou, Eleni</creatorcontrib><creatorcontrib>Kofina, Konstantinia</creatorcontrib><creatorcontrib>Giatromanolaki, Alexandra</creatorcontrib><creatorcontrib>Chatzipantelis, Paschalis</creatorcontrib><creatorcontrib>Karanikas, Michael</creatorcontrib><creatorcontrib>Lyratzopoulos, Nicolaos</creatorcontrib><title>Primary ectopic Merkel cell carcinoma without skin involvement—report of a case with prolonged survival</title><title>Journal of surgical case reports</title><description>Abstract Merkel cell carcinoma is a rare neuroendocrine malignancy that arises from the dermis, in cases of immunocompromised, middle-aged patients or on skin exposed to sunlight. It only rarely presents in extra-cutaneous locations. We present the case of a 63-year-old female with a mass in the adipose tissue of the upper arm, without skin involvement and concurrent axillary lymph node enlargement. She was treated with wide excision and lymph node dissection; pathology led to the diagnosis of Merkel cell carcinoma, and she was subsequently submitted to adjuvant radiotherapy. No signs of recurrence are present 8 years postoperatively. Primary Merkel cell carcinoma can rarely be located in the adipose tissue without skin involvement. In cases of high suspicion, preoperative MRI scan can show the extent of the lesion, as well as lymph metastases.</description><subject>Case Report</subject><issn>2042-8812</issn><issn>2042-8812</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><recordid>eNp9UMtOwzAQtBCIVqU3PsA3LoR6bTdOLkio4iUVwQHOkeM4rdskjuwkiBsfwRfyJaSkQnBhD7sr7cxoZxA6BXIBJGazjVdu5jZSspgcoDElnAZRBPTw1z5CU-83pC8eA0ThMRoxBiGDORsj8-RMKd0b1qqxtVH4QbutLrDSRd-kU6aypcSvplnbtsF-aypsqs4WnS511Xy-fzhdW9dgm2PZE7z-xuLa2cJWK51h37rOdLI4QUe5LLye7ucEvdxcPy_uguXj7f3iahkoBqIJuAQBhGqehwqIBJlxxUWUMyIF5TxiYUQ5iIymGnoL6RximcWUCBGJPM9TNkGXg27dpqXOVP-lk0VSDz4TK03y91KZdbKyXSJCMqcgeoHzQUA5673T-Q8XSLJLPdmlnuxT7-FnA9y29f_IL-DJhrM</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Effraimidou, Eleni</creator><creator>Kofina, Konstantinia</creator><creator>Giatromanolaki, Alexandra</creator><creator>Chatzipantelis, Paschalis</creator><creator>Karanikas, Michael</creator><creator>Lyratzopoulos, Nicolaos</creator><general>Oxford University Press</general><scope>TOX</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8052-2807</orcidid></search><sort><creationdate>20201001</creationdate><title>Primary ectopic Merkel cell carcinoma without skin involvement—report of a case with prolonged survival</title><author>Effraimidou, Eleni ; Kofina, Konstantinia ; Giatromanolaki, Alexandra ; Chatzipantelis, Paschalis ; Karanikas, Michael ; Lyratzopoulos, Nicolaos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c317t-4a17102e4f6c10a1ad4c478f30a724483682417d2be1315b519ad9207787fffb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Case Report</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Effraimidou, Eleni</creatorcontrib><creatorcontrib>Kofina, Konstantinia</creatorcontrib><creatorcontrib>Giatromanolaki, Alexandra</creatorcontrib><creatorcontrib>Chatzipantelis, Paschalis</creatorcontrib><creatorcontrib>Karanikas, Michael</creatorcontrib><creatorcontrib>Lyratzopoulos, Nicolaos</creatorcontrib><collection>Oxford Journals Open Access Collection</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of surgical case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Effraimidou, Eleni</au><au>Kofina, Konstantinia</au><au>Giatromanolaki, Alexandra</au><au>Chatzipantelis, Paschalis</au><au>Karanikas, Michael</au><au>Lyratzopoulos, Nicolaos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary ectopic Merkel cell carcinoma without skin involvement—report of a case with prolonged survival</atitle><jtitle>Journal of surgical case reports</jtitle><date>2020-10-01</date><risdate>2020</risdate><volume>2020</volume><issue>10</issue><issn>2042-8812</issn><eissn>2042-8812</eissn><abstract>Abstract Merkel cell carcinoma is a rare neuroendocrine malignancy that arises from the dermis, in cases of immunocompromised, middle-aged patients or on skin exposed to sunlight. It only rarely presents in extra-cutaneous locations. We present the case of a 63-year-old female with a mass in the adipose tissue of the upper arm, without skin involvement and concurrent axillary lymph node enlargement. She was treated with wide excision and lymph node dissection; pathology led to the diagnosis of Merkel cell carcinoma, and she was subsequently submitted to adjuvant radiotherapy. No signs of recurrence are present 8 years postoperatively. Primary Merkel cell carcinoma can rarely be located in the adipose tissue without skin involvement. In cases of high suspicion, preoperative MRI scan can show the extent of the lesion, as well as lymph metastases.</abstract><pub>Oxford University Press</pub><pmid>33163153</pmid><doi>10.1093/jscr/rjaa390</doi><orcidid>https://orcid.org/0000-0002-8052-2807</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2042-8812
ispartof Journal of surgical case reports, 2020-10, Vol.2020 (10)
issn 2042-8812
2042-8812
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7605217
source Oxford Journals Open Access Collection; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Case Report
title Primary ectopic Merkel cell carcinoma without skin involvement—report of a case with prolonged survival
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T22%3A42%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-oup_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Primary%20ectopic%20Merkel%20cell%20carcinoma%20without%20skin%20involvement%E2%80%94report%20of%20a%20case%20with%20prolonged%20survival&rft.jtitle=Journal%20of%20surgical%20case%20reports&rft.au=Effraimidou,%20Eleni&rft.date=2020-10-01&rft.volume=2020&rft.issue=10&rft.issn=2042-8812&rft.eissn=2042-8812&rft_id=info:doi/10.1093/jscr/rjaa390&rft_dat=%3Coup_pubme%3E10.1093/jscr/rjaa390%3C/oup_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/33163153&rft_oup_id=10.1093/jscr/rjaa390&rfr_iscdi=true