Vaccination in multiple sclerosis ‑ Challenging practices (Review)
Infections are an ever-present problem in the medical community, even more so for patients with multiple sclerosis (MS), for whom these infections have been linked to relapses and neurological disabilities. Even though it was believed that MS can be caused by an infection, research does not support...
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Veröffentlicht in: | Experimental and therapeutic medicine 2020-12, Vol.20 (6), p.1-1 |
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creator | Sirbu, Carmen Adella Florea, Anca Alexandra Ghinescu, Minerva Claudia Docu-Axelerad, Any Sirbu, Anca Maria Bratu, Ovidiu Gabriel Radu, Florentina Ionita |
description | Infections are an ever-present problem in the medical community, even more so for patients with multiple sclerosis (MS), for whom these infections have been linked to relapses and neurological disabilities. Even though it was believed that MS can be caused by an infection, research does not support this theory. MS is a chronic inflammatory disease considered to be autoimmune. Vaccination is proven to be one of the most effective means to prevent infections, but still it is surrounded by controversy in the general populations, as well as in the MS group. Vaccines are generally considered safe for MS patients. The exceptions from this, which turn into contraindications, are a medical history of allergic reactions to one of the vaccine components and immunosuppressed patients in the particular case of live vaccines. Given the presumed autoimmunity of the disease, some medication for MS is immunosuppressive and any live vaccine should be administered before starting treatment. Although there is still confusion regarding this subject, the current guidelines have clearer recommendations about vaccinations in MS patients and especially in treated MS patients. |
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Even though it was believed that MS can be caused by an infection, research does not support this theory. MS is a chronic inflammatory disease considered to be autoimmune. Vaccination is proven to be one of the most effective means to prevent infections, but still it is surrounded by controversy in the general populations, as well as in the MS group. Vaccines are generally considered safe for MS patients. The exceptions from this, which turn into contraindications, are a medical history of allergic reactions to one of the vaccine components and immunosuppressed patients in the particular case of live vaccines. Given the presumed autoimmunity of the disease, some medication for MS is immunosuppressive and any live vaccine should be administered before starting treatment. Although there is still confusion regarding this subject, the current guidelines have clearer recommendations about vaccinations in MS patients and especially in treated MS patients.</description><identifier>ISSN: 1792-0981</identifier><identifier>EISSN: 1792-1015</identifier><identifier>DOI: 10.3892/etm.2020.9347</identifier><identifier>PMID: 33149781</identifier><language>eng</language><publisher>Athens: Spandidos Publications</publisher><subject>Aluminum ; Antibodies ; Antigens ; Autoimmune diseases ; Care and treatment ; Disease ; Genetic engineering ; Hepatitis B ; Human papillomavirus ; Immune system ; Infection ; Infections ; Influenza ; Lymphocytes ; Measles ; Methods ; Multiple sclerosis ; Mumps ; Pathogens ; Poliomyelitis ; Prevention ; Proteins ; Review ; Rubella ; Tetanus ; Tropical diseases ; Typhoid ; Vaccination ; Vaccines ; Whooping cough</subject><ispartof>Experimental and therapeutic medicine, 2020-12, Vol.20 (6), p.1-1</ispartof><rights>COPYRIGHT 2020 Spandidos Publications</rights><rights>Copyright Spandidos Publications UK Ltd. 2020</rights><rights>Copyright © 2020, Spandidos Publications 2020</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-928bad0a41debb23184af2778bf20d9f604ce83cfd54003cc196c6caa2ab1ebb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604740/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604740/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids></links><search><creatorcontrib>Sirbu, Carmen Adella</creatorcontrib><creatorcontrib>Florea, Anca Alexandra</creatorcontrib><creatorcontrib>Ghinescu, Minerva Claudia</creatorcontrib><creatorcontrib>Docu-Axelerad, Any</creatorcontrib><creatorcontrib>Sirbu, Anca Maria</creatorcontrib><creatorcontrib>Bratu, Ovidiu Gabriel</creatorcontrib><creatorcontrib>Radu, Florentina Ionita</creatorcontrib><title>Vaccination in multiple sclerosis ‑ Challenging practices (Review)</title><title>Experimental and therapeutic medicine</title><description>Infections are an ever-present problem in the medical community, even more so for patients with multiple sclerosis (MS), for whom these infections have been linked to relapses and neurological disabilities. Even though it was believed that MS can be caused by an infection, research does not support this theory. MS is a chronic inflammatory disease considered to be autoimmune. Vaccination is proven to be one of the most effective means to prevent infections, but still it is surrounded by controversy in the general populations, as well as in the MS group. Vaccines are generally considered safe for MS patients. The exceptions from this, which turn into contraindications, are a medical history of allergic reactions to one of the vaccine components and immunosuppressed patients in the particular case of live vaccines. Given the presumed autoimmunity of the disease, some medication for MS is immunosuppressive and any live vaccine should be administered before starting treatment. Although there is still confusion regarding this subject, the current guidelines have clearer recommendations about vaccinations in MS patients and especially in treated MS patients.</description><subject>Aluminum</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Autoimmune diseases</subject><subject>Care and treatment</subject><subject>Disease</subject><subject>Genetic engineering</subject><subject>Hepatitis B</subject><subject>Human papillomavirus</subject><subject>Immune system</subject><subject>Infection</subject><subject>Infections</subject><subject>Influenza</subject><subject>Lymphocytes</subject><subject>Measles</subject><subject>Methods</subject><subject>Multiple sclerosis</subject><subject>Mumps</subject><subject>Pathogens</subject><subject>Poliomyelitis</subject><subject>Prevention</subject><subject>Proteins</subject><subject>Review</subject><subject>Rubella</subject><subject>Tetanus</subject><subject>Tropical diseases</subject><subject>Typhoid</subject><subject>Vaccination</subject><subject>Vaccines</subject><subject>Whooping cough</subject><issn>1792-0981</issn><issn>1792-1015</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNptkc9qFTEUxoMottQu3Q900y7mNv9mkmwK5apVKAiibkPmzJnblExyO5mpuPMVfEWfpLn0YqmYLHJIvu9LTn6EvGV0JbTh5ziPK045XRkh1QtyyJThNaOsebmvqdHsgBznfEvLaFqmdfOaHAjBpFGaHZJ33x2Aj272KVY-VuMSZr8NWGUIOKXsc_Xn1-9qfeNCwLjxcVNtJwezB8zV6Re89_jj7A15NbiQ8Xi_HpFvH95_XX-srz9ffVpfXtdQXjvXhuvO9dRJ1mPXccG0dANXSncDp70ZWioBtYChbySlAoCZFlpwjruOFYc4IhePudulG7EHjPPkgt1OfnTTT5uct89Por-xm3RvVYlWkpaA033AlO4WzLMdfQYMwUVMS7ZcNsq0SsimSE_-kd6mZYqlvaJqRflL1agn1cYFtD4OqdwLu1B72cpWa1kAFNXqP6oyexw9pIiDL_vPDPWjAQqCPOHwt0dG7Y68LeTtjrzdkRcPmjifzA</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Sirbu, Carmen Adella</creator><creator>Florea, Anca Alexandra</creator><creator>Ghinescu, Minerva Claudia</creator><creator>Docu-Axelerad, Any</creator><creator>Sirbu, Anca Maria</creator><creator>Bratu, Ovidiu Gabriel</creator><creator>Radu, Florentina Ionita</creator><general>Spandidos Publications</general><general>Spandidos Publications UK Ltd</general><general>D.A. 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Even though it was believed that MS can be caused by an infection, research does not support this theory. MS is a chronic inflammatory disease considered to be autoimmune. Vaccination is proven to be one of the most effective means to prevent infections, but still it is surrounded by controversy in the general populations, as well as in the MS group. Vaccines are generally considered safe for MS patients. The exceptions from this, which turn into contraindications, are a medical history of allergic reactions to one of the vaccine components and immunosuppressed patients in the particular case of live vaccines. Given the presumed autoimmunity of the disease, some medication for MS is immunosuppressive and any live vaccine should be administered before starting treatment. Although there is still confusion regarding this subject, the current guidelines have clearer recommendations about vaccinations in MS patients and especially in treated MS patients.</abstract><cop>Athens</cop><pub>Spandidos Publications</pub><pmid>33149781</pmid><doi>10.3892/etm.2020.9347</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aluminum Antibodies Antigens Autoimmune diseases Care and treatment Disease Genetic engineering Hepatitis B Human papillomavirus Immune system Infection Infections Influenza Lymphocytes Measles Methods Multiple sclerosis Mumps Pathogens Poliomyelitis Prevention Proteins Review Rubella Tetanus Tropical diseases Typhoid Vaccination Vaccines Whooping cough |
title | Vaccination in multiple sclerosis ‑ Challenging practices (Review) |
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