Evaluation of miR-34a Effect on CCND1 mRNA Level and Sensitization of Breast Cancer Cell Lines to Paclitaxel

Background: A growing body of literature has revealed the effective role of miR-34a, as a tumor suppressor and regulator of expression of multiple targets in tumorigenesis and cancer progression. This study aimed at evaluating the potential effects of miR-34a alone or in combination with paclitaxel...

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Veröffentlicht in:	Iranian biomedical journal 2020-10, Vol.24 (6), p.361-364
Hauptverfasser:	Irani, Shiva, Paknejad, Mahsa, Soleimani, Masoud, Soleimani, Azam
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Breast cancer Cell cycle Cell proliferation Cell viability Combined treatment Cyclin D1 Evaluation Flow cytometry Full Length Gene expression Paclitaxel Tumor cell lines Tumor suppressor genes Tumorigenesis
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