Extracellular Vesicles as Biomarkers in Cancer Immunotherapy

Extracellular vesicles (EVs), including exosomes and microvesicles, are membrane-bound vesicles secreted by most cell types during both physiologic conditions as well in response to cellular stress. EVs play an important role in intercellular communication and are emerging as key players in tumor im...

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Veröffentlicht in:	Cancers 2020-09, Vol.12 (10), p.2825
Hauptverfasser:	Mathew, Matthen, Zade, Mariam, Mezghani, Nadia, Patel, Romil, Wang, Yu, Momen-Heravi, Fatemeh
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic fluid Antibodies Antitumor activity Apoptosis Biomarkers Biopsy Cancer immunotherapy Cell interactions Cell signaling Diagnosis Exosomes Extracellular vesicles Gene expression Head & neck cancer Immune response Immunotherapy Lung cancer Lung carcinoma Lymphocytes Melanoma Membrane vesicles Metastasis MicroRNAs Mutation Neoantigens Non-small cell lung carcinoma Patient outcomes Patients PD-1 protein PD-L1 protein Response rates Review Saliva Small cell lung carcinoma Solid tumors Squamous cell carcinoma Therapeutic applications Tumor microenvironment Tumors
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