Complete Loss of EPCAM Immunoexpression Identifies EPCAM Deletion Carriers in MSH2-Negative Colorectal Neoplasia

The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. The aim of the present study was to demonstrate that EPCAM IHC is a useful tool to guide the LS germ-line analysi...

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Veröffentlicht in:	Cancers 2020-09, Vol.12 (10), p.2803
Hauptverfasser:	Cuatrecasas, Míriam, Gorostiaga, Iñigo, Riera, Cristina, Saperas, Esteban, Llort, Gemma, Costa, Irmgard, Matias-Guiu, Xavier, Carrato, Cristina, Navarro, Matilde, Pineda, Marta, Dueñas, Núria, Brunet, Joan, Marco, Vicente, Trias, Isabel, Busteros, José Ignacio, Mateu, Gemma, Balaguer, Francesc, Fernández-Figueras, María-Teresa, Esteller, Manel, Musulén, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Cancer Cell adhesion molecules Colon Colorectal cancer Colorectal carcinoma Endometrium Epithelial cells Gene expression Genes Genetic aspects Health aspects Histology Immunohistochemistry Lesions MSH2 protein Mutation Neoplasia Pancreas Polyps Prostate Thyroid gland Tumors
Online-Zugang:	Volltext
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