Kupffer Cells: Inflammation Pathways and Cell-Cell Interactions in Alcohol-Associated Liver Disease

Chronic alcohol consumption is linked to the development of alcohol-associated liver disease (ALD). This disease is characterized by a clinical spectrum ranging from steatosis to hepatocellular carcinoma. Several cell types are involved in ALD progression, including hepatic macrophages. Kupffer cell...

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Veröffentlicht in:	The American journal of pathology 2020-11, Vol.190 (11), p.2185-2193
Hauptverfasser:	Slevin, Elise, Baiocchi, Leonardo, Wu, Nan, Ekser, Burcin, Sato, Keisaku, Lin, Emily, Ceci, Ludovica, Chen, Lixian, Lorenzo, Sugeily R, Xu, Wenjuan, Kyritsi, Konstantina, Meadows, Victoria, Zhou, Tianhao, Kundu, Debiyoti, Han, Yuyan, Kennedy, Lindsey, Glaser, Shannon, Francis, Heather, Alpini, Gianfranco, Meng, Fanyin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Communication Chemokines - metabolism Disease Models, Animal Hepatic Stellate Cells - metabolism Hepatic Stellate Cells - pathology Humans Kupffer Cells - metabolism Kupffer Cells - pathology Liver - metabolism Liver - pathology Liver Diseases, Alcoholic - metabolism Liver Diseases, Alcoholic - pathology Mice Reactive Oxygen Species - metabolism Review
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