Oral administration of the iron chelator deferiprone protects against loss of retinal ganglion cells in a mouse model of glaucoma

Glaucoma is a progressive neurodegenerative process affecting the retinal ganglion cells (RGCs) and the optic nerve. Oxidative stress has been implicated in glaucoma pathogenesis, and iron is a potent generator of oxidative stress. The oral iron chelator deferiprone (DFP) is protective against retin...

Ausführliche Beschreibung