An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum
Abstract Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal strom...
Gespeichert in:
| Veröffentlicht in: | Oxford Medical Case Reports 2020-10, Vol.2020 (10), p.353 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 10 |
| container_start_page | 353 |
| container_title | Oxford Medical Case Reports |
| container_volume | 2020 |
| creator | Zainudin, Syaza Rajanthran, Saravana Kumar Azizan, Nornazirah Hayati, Firdaus Ginawoi, Joriana Suhaimi, Khairunnisa Aini Voo, Wan Yee Lilian Kiram, Mohd Fazri Md Jaki, Muhammad Izzuddin Abd Aziz, Siti Haja Nacathiran, Subashini Thevi Nach |
| description | Abstract
Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal stromal tumour (GIST) histologically. We report a case of a 30-year-old gentleman who presented with a huge painful mass in the right iliac fossa. Computed tomography revealed a 10 × 10 cm homogeneous mass arising from the terminal ileum; he subsequently underwent an open right hemicolectomy. Histology showed a well-circumscribed lesion composed of interlacing bundles of smooth muscle fibres of the submucosa with positive smooth muscle actin and H-Caldesmon stains but negative for DOG-1 and CD117 (c-kit) stains which were consistent with leiomyoma. Despite its rarity, this hormone-related tumour needs to be considered regardless of gender. Immunohistochemistry is paramount as it is histologically identical to GIST. |
| doi_str_mv | 10.1093/omcr/omaa086 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7583423</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A649131301</galeid><oup_id>10.1093/omcr/omaa086</oup_id><sourcerecordid>A649131301</sourcerecordid><originalsourceid>FETCH-LOGICAL-c427t-9295ac8e689b3294626971c2dad101a662d14744c9eca4afff8c338fbd5154b23</originalsourceid><addsrcrecordid>eNp9kctKxDAUhoMozjDOzgfIzo0dc2ubbIRh8AYDbtRtSNOkjTRN6UWZtzdDRXQjgVy_85-c8wNwidEGI0Fvgtd9nJRCPDsBS4JSmnCepqe_9guwHoZ3hBCmGaacn4MFpZjGg1iCt20LQ6tDEyqnVQP11LswuPEAg4UKetUY2KnRmXaEn26s4109VQY2xgV_iJmP3FgbOJreuzYquMZM_gKcWdUMZv29rsDr_d3L7jHZPz887bb7RDOSj4kgIlWam4yLghLBMpKJHGtSqhIjrLKMlJjljGlhtGLKWss1pdwWZYpTVhC6ArezbjcV3pQ6frNXjex651V_kEE5-feldbWswofMU04ZoVFgMwtUsVLpWhsipuMojXc6tMbGeuQ2YwLHnsUWrsD1HKD7MAy9sT_JMJJHT-TRE_ntScSvZjxM3f_kF7ipjgA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum</title><source>Oxford Journals Open Access Collection</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Zainudin, Syaza ; Rajanthran, Saravana Kumar ; Azizan, Nornazirah ; Hayati, Firdaus ; Ginawoi, Joriana ; Suhaimi, Khairunnisa Aini ; Voo, Wan Yee Lilian ; Kiram, Mohd Fazri ; Md Jaki, Muhammad Izzuddin ; Abd Aziz, Siti Haja ; Nacathiran, Subashini Thevi Nach</creator><creatorcontrib>Zainudin, Syaza ; Rajanthran, Saravana Kumar ; Azizan, Nornazirah ; Hayati, Firdaus ; Ginawoi, Joriana ; Suhaimi, Khairunnisa Aini ; Voo, Wan Yee Lilian ; Kiram, Mohd Fazri ; Md Jaki, Muhammad Izzuddin ; Abd Aziz, Siti Haja ; Nacathiran, Subashini Thevi Nach</creatorcontrib><description>Abstract
Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal stromal tumour (GIST) histologically. We report a case of a 30-year-old gentleman who presented with a huge painful mass in the right iliac fossa. Computed tomography revealed a 10 × 10 cm homogeneous mass arising from the terminal ileum; he subsequently underwent an open right hemicolectomy. Histology showed a well-circumscribed lesion composed of interlacing bundles of smooth muscle fibres of the submucosa with positive smooth muscle actin and H-Caldesmon stains but negative for DOG-1 and CD117 (c-kit) stains which were consistent with leiomyoma. Despite its rarity, this hormone-related tumour needs to be considered regardless of gender. Immunohistochemistry is paramount as it is histologically identical to GIST.</description><identifier>ISSN: 2053-8855</identifier><identifier>EISSN: 2053-8855</identifier><identifier>DOI: 10.1093/omcr/omaa086</identifier><identifier>PMID: 33133619</identifier><language>eng</language><publisher>Oxford University Press</publisher><subject>Case Report ; Case studies ; Diagnosis ; Leiomyoma</subject><ispartof>Oxford Medical Case Reports, 2020-10, Vol.2020 (10), p.353</ispartof><rights>The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2020</rights><rights>COPYRIGHT 2020 Oxford University Press</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-9295ac8e689b3294626971c2dad101a662d14744c9eca4afff8c338fbd5154b23</citedby><cites>FETCH-LOGICAL-c427t-9295ac8e689b3294626971c2dad101a662d14744c9eca4afff8c338fbd5154b23</cites><orcidid>0000-0002-3757-9744</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583423/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583423/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1598,27903,27904,53769,53771</link.rule.ids></links><search><creatorcontrib>Zainudin, Syaza</creatorcontrib><creatorcontrib>Rajanthran, Saravana Kumar</creatorcontrib><creatorcontrib>Azizan, Nornazirah</creatorcontrib><creatorcontrib>Hayati, Firdaus</creatorcontrib><creatorcontrib>Ginawoi, Joriana</creatorcontrib><creatorcontrib>Suhaimi, Khairunnisa Aini</creatorcontrib><creatorcontrib>Voo, Wan Yee Lilian</creatorcontrib><creatorcontrib>Kiram, Mohd Fazri</creatorcontrib><creatorcontrib>Md Jaki, Muhammad Izzuddin</creatorcontrib><creatorcontrib>Abd Aziz, Siti Haja</creatorcontrib><creatorcontrib>Nacathiran, Subashini Thevi Nach</creatorcontrib><title>An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum</title><title>Oxford Medical Case Reports</title><description>Abstract
Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal stromal tumour (GIST) histologically. We report a case of a 30-year-old gentleman who presented with a huge painful mass in the right iliac fossa. Computed tomography revealed a 10 × 10 cm homogeneous mass arising from the terminal ileum; he subsequently underwent an open right hemicolectomy. Histology showed a well-circumscribed lesion composed of interlacing bundles of smooth muscle fibres of the submucosa with positive smooth muscle actin and H-Caldesmon stains but negative for DOG-1 and CD117 (c-kit) stains which were consistent with leiomyoma. Despite its rarity, this hormone-related tumour needs to be considered regardless of gender. Immunohistochemistry is paramount as it is histologically identical to GIST.</description><subject>Case Report</subject><subject>Case studies</subject><subject>Diagnosis</subject><subject>Leiomyoma</subject><issn>2053-8855</issn><issn>2053-8855</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><recordid>eNp9kctKxDAUhoMozjDOzgfIzo0dc2ubbIRh8AYDbtRtSNOkjTRN6UWZtzdDRXQjgVy_85-c8wNwidEGI0Fvgtd9nJRCPDsBS4JSmnCepqe_9guwHoZ3hBCmGaacn4MFpZjGg1iCt20LQ6tDEyqnVQP11LswuPEAg4UKetUY2KnRmXaEn26s4109VQY2xgV_iJmP3FgbOJreuzYquMZM_gKcWdUMZv29rsDr_d3L7jHZPz887bb7RDOSj4kgIlWam4yLghLBMpKJHGtSqhIjrLKMlJjljGlhtGLKWss1pdwWZYpTVhC6ArezbjcV3pQ6frNXjex651V_kEE5-feldbWswofMU04ZoVFgMwtUsVLpWhsipuMojXc6tMbGeuQ2YwLHnsUWrsD1HKD7MAy9sT_JMJJHT-TRE_ntScSvZjxM3f_kF7ipjgA</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Zainudin, Syaza</creator><creator>Rajanthran, Saravana Kumar</creator><creator>Azizan, Nornazirah</creator><creator>Hayati, Firdaus</creator><creator>Ginawoi, Joriana</creator><creator>Suhaimi, Khairunnisa Aini</creator><creator>Voo, Wan Yee Lilian</creator><creator>Kiram, Mohd Fazri</creator><creator>Md Jaki, Muhammad Izzuddin</creator><creator>Abd Aziz, Siti Haja</creator><creator>Nacathiran, Subashini Thevi Nach</creator><general>Oxford University Press</general><scope>TOX</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IAO</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-3757-9744</orcidid></search><sort><creationdate>20201001</creationdate><title>An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum</title><author>Zainudin, Syaza ; Rajanthran, Saravana Kumar ; Azizan, Nornazirah ; Hayati, Firdaus ; Ginawoi, Joriana ; Suhaimi, Khairunnisa Aini ; Voo, Wan Yee Lilian ; Kiram, Mohd Fazri ; Md Jaki, Muhammad Izzuddin ; Abd Aziz, Siti Haja ; Nacathiran, Subashini Thevi Nach</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-9295ac8e689b3294626971c2dad101a662d14744c9eca4afff8c338fbd5154b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Case Report</topic><topic>Case studies</topic><topic>Diagnosis</topic><topic>Leiomyoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zainudin, Syaza</creatorcontrib><creatorcontrib>Rajanthran, Saravana Kumar</creatorcontrib><creatorcontrib>Azizan, Nornazirah</creatorcontrib><creatorcontrib>Hayati, Firdaus</creatorcontrib><creatorcontrib>Ginawoi, Joriana</creatorcontrib><creatorcontrib>Suhaimi, Khairunnisa Aini</creatorcontrib><creatorcontrib>Voo, Wan Yee Lilian</creatorcontrib><creatorcontrib>Kiram, Mohd Fazri</creatorcontrib><creatorcontrib>Md Jaki, Muhammad Izzuddin</creatorcontrib><creatorcontrib>Abd Aziz, Siti Haja</creatorcontrib><creatorcontrib>Nacathiran, Subashini Thevi Nach</creatorcontrib><collection>Oxford Journals Open Access Collection</collection><collection>CrossRef</collection><collection>Gale Academic OneFile</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Oxford Medical Case Reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zainudin, Syaza</au><au>Rajanthran, Saravana Kumar</au><au>Azizan, Nornazirah</au><au>Hayati, Firdaus</au><au>Ginawoi, Joriana</au><au>Suhaimi, Khairunnisa Aini</au><au>Voo, Wan Yee Lilian</au><au>Kiram, Mohd Fazri</au><au>Md Jaki, Muhammad Izzuddin</au><au>Abd Aziz, Siti Haja</au><au>Nacathiran, Subashini Thevi Nach</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum</atitle><jtitle>Oxford Medical Case Reports</jtitle><date>2020-10-01</date><risdate>2020</risdate><volume>2020</volume><issue>10</issue><spage>353</spage><pages>353-</pages><issn>2053-8855</issn><eissn>2053-8855</eissn><abstract>Abstract
Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal stromal tumour (GIST) histologically. We report a case of a 30-year-old gentleman who presented with a huge painful mass in the right iliac fossa. Computed tomography revealed a 10 × 10 cm homogeneous mass arising from the terminal ileum; he subsequently underwent an open right hemicolectomy. Histology showed a well-circumscribed lesion composed of interlacing bundles of smooth muscle fibres of the submucosa with positive smooth muscle actin and H-Caldesmon stains but negative for DOG-1 and CD117 (c-kit) stains which were consistent with leiomyoma. Despite its rarity, this hormone-related tumour needs to be considered regardless of gender. Immunohistochemistry is paramount as it is histologically identical to GIST.</abstract><pub>Oxford University Press</pub><pmid>33133619</pmid><doi>10.1093/omcr/omaa086</doi><orcidid>https://orcid.org/0000-0002-3757-9744</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2053-8855 |
| ispartof | Oxford Medical Case Reports, 2020-10, Vol.2020 (10), p.353 |
| issn | 2053-8855 2053-8855 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7583423 |
| source | Oxford Journals Open Access Collection; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Case Report Case studies Diagnosis Leiomyoma |
| title | An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T17%3A42%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20oncological%20curiosity%20of%20a%20male%20patient%20with%20a%20huge%20leiomyoma%20of%20the%20terminal%20ileum&rft.jtitle=Oxford%20Medical%20Case%20Reports&rft.au=Zainudin,%20Syaza&rft.date=2020-10-01&rft.volume=2020&rft.issue=10&rft.spage=353&rft.pages=353-&rft.issn=2053-8855&rft.eissn=2053-8855&rft_id=info:doi/10.1093/omcr/omaa086&rft_dat=%3Cgale_pubme%3EA649131301%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/33133619&rft_galeid=A649131301&rft_oup_id=10.1093/omcr/omaa086&rfr_iscdi=true |