A rapid and highly sensitive biomarker detection platform based on a temperature-responsive liposome-linked immunosorbent assay

The enzyme-linked immunosorbent assay (ELISA) is widely used in various fields to detect specific biomarkers. However, ELISA tests have limited detection sensitivity (≥ 1 pM), which is insufficiently sensitive for the detection of small amounts of biomarkers in the early stages of disease or infecti...

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Veröffentlicht in:	Scientific reports 2020-10, Vol.10 (1), p.18086-18086, Article 18086
Hauptverfasser:	Hu, Runkai, Sou, Keitaro, Takeoka, Shinji
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/664/1467 631/61/350 639/638/11/874 Antibodies - immunology Antigens Biomarkers Biomarkers - analysis Enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Fluorescence Humanities and Social Sciences Humans Immunosorbents - chemistry Limit of Detection Liposomes Liposomes - chemistry multidisciplinary Phase transitions Prostate Prostate-Specific Antigen - analysis Science Science (multidisciplinary) Streptavidin Temperature Transition temperatures
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