Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review)

At present, irritable bowel syndrome (IBS) is a common medical problem all over the world that implies considerable social burden and high costs. Considering the different pathophysiological pathways, unitary management for IBS is not possible. Of the therapeutic approaches that have been proposed s...

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Veröffentlicht in:Experimental and therapeutic medicine 2020-12, Vol.20 (6), p.1-1
Hauptverfasser: Barboi, Oana-bogdana, Ciortescu, Irina, Chirila, Ioan, Anton, Carmen, Drug, Vasile
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container_end_page 1
container_issue 6
container_start_page 1
container_title Experimental and therapeutic medicine
container_volume 20
creator Barboi, Oana-bogdana
Ciortescu, Irina
Chirila, Ioan
Anton, Carmen
Drug, Vasile
description At present, irritable bowel syndrome (IBS) is a common medical problem all over the world that implies considerable social burden and high costs. Considering the different pathophysiological pathways, unitary management for IBS is not possible. Of the therapeutic approaches that have been proposed so far, only a few have been demonstrated to have beneficial effects in IBS patients. The implication of gut microbiota in IBS is obvious, similarly to the therapeutic effect of pro-/prebiotics, which is reflected by the latest publications. The intake of inulin seems to regulate the bowel peristalsis and colonic transit, the consistency and frequency of the stools, as it changes the composition of gut microbiota. The beneficial effect of inulin in patients with IBS-constipation form (IBS-C) is obvious, but still, more randomized controlled clinical trials involving large samples of patients are needed in order to provide more evidence.
doi_str_mv 10.3892/etm.2020.9315
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subjects Bacteria
Care and treatment
Chronic illnesses
Clinical trials
Colon
Constipation
Dietary fiber
FDA approval
Food
Inulin
Irritable bowel syndrome
Microbiota
Prebiotics
Quality of life
Review
Yogurt
title Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review)
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