Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer
The study aimed to evaluate the effects of chemotherapy treatment on muscle strength, quality of life, fatigue, and anxiety in women with breast cancer. Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (c...
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| Veröffentlicht in: | International journal of environmental research and public health 2020-10, Vol.17 (19), p.7289 |
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| creator | Marques, Vitor A Ferreira-Junior, João B Lemos, Thiago V Moraes, Rafael F Junior, José Roberto de S Alves, Rafael R Silva, Maria S Freitas-Junior, Ruffo de Vieira, Carlos A |
| description | The study aimed to evaluate the effects of chemotherapy treatment on muscle strength, quality of life, fatigue, and anxiety in women with breast cancer. Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (control [CNT] group, 55.8 ± 8.4 years) answered questionnaires for evaluation of fatigue (Fatigue Scale), quality of life (Short-Form Healthy Survey [SF-36] questionnaire), and anxiety (State-Trait Anxiety Inventory [IDATE]) levels. Muscle strength was also assessed by an isometric grip test and an isokinetic knee extension test. Physical limitations, social and emotional domains of quality of life were lower in the BCT group in comparison to the CNT group (
= 0.002;
= 0.003;
= 0.0003, respectively). The other domains did not differ between groups (
> 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups (
> 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group (
= 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s
(
= 0.95 and
= 0.61, respectively) and 180°.s
(
= 0.94 and
= 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer. |
| doi_str_mv | 10.3390/ijerph17197289 |
| format | Article |
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= 0.002;
= 0.003;
= 0.0003, respectively). The other domains did not differ between groups (
> 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups (
> 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group (
= 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s
(
= 0.95 and
= 0.61, respectively) and 180°.s
(
= 0.94 and
= 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph17197289</identifier><identifier>PMID: 33036182</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Anxiety ; Breast cancer ; Breast Neoplasms ; Cancer therapies ; Chemotherapy ; Domains ; Drug Therapy ; Evaluation ; Exercise ; Fatigue ; Female ; Grip strength ; Hand Strength ; Health care ; Humans ; Muscle contraction ; Muscle Strength ; Muscular fatigue ; Physical fitness ; Quality of Life ; Questionnaires ; Standard deviation ; Statistical analysis ; Values ; Women ; Womens health</subject><ispartof>International journal of environmental research and public health, 2020-10, Vol.17 (19), p.7289</ispartof><rights>2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 by the authors. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-b0c1657b073e5117a7b8418eb0b7521dcfb3a824ec615dbc1ccccd65c88de96f3</citedby><cites>FETCH-LOGICAL-c418t-b0c1657b073e5117a7b8418eb0b7521dcfb3a824ec615dbc1ccccd65c88de96f3</cites><orcidid>0000-0003-4145-8598 ; 0000-0002-0866-6777 ; 0000-0002-0083-2910 ; 0000-0002-7541-8212</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579368/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579368/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33036182$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Marques, Vitor A</creatorcontrib><creatorcontrib>Ferreira-Junior, João B</creatorcontrib><creatorcontrib>Lemos, Thiago V</creatorcontrib><creatorcontrib>Moraes, Rafael F</creatorcontrib><creatorcontrib>Junior, José Roberto de S</creatorcontrib><creatorcontrib>Alves, Rafael R</creatorcontrib><creatorcontrib>Silva, Maria S</creatorcontrib><creatorcontrib>Freitas-Junior, Ruffo de</creatorcontrib><creatorcontrib>Vieira, Carlos A</creatorcontrib><title>Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>The study aimed to evaluate the effects of chemotherapy treatment on muscle strength, quality of life, fatigue, and anxiety in women with breast cancer. Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (control [CNT] group, 55.8 ± 8.4 years) answered questionnaires for evaluation of fatigue (Fatigue Scale), quality of life (Short-Form Healthy Survey [SF-36] questionnaire), and anxiety (State-Trait Anxiety Inventory [IDATE]) levels. Muscle strength was also assessed by an isometric grip test and an isokinetic knee extension test. Physical limitations, social and emotional domains of quality of life were lower in the BCT group in comparison to the CNT group (
= 0.002;
= 0.003;
= 0.0003, respectively). The other domains did not differ between groups (
> 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups (
> 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group (
= 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s
(
= 0.95 and
= 0.61, respectively) and 180°.s
(
= 0.94 and
= 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer.</description><subject>Anxiety</subject><subject>Breast cancer</subject><subject>Breast Neoplasms</subject><subject>Cancer therapies</subject><subject>Chemotherapy</subject><subject>Domains</subject><subject>Drug Therapy</subject><subject>Evaluation</subject><subject>Exercise</subject><subject>Fatigue</subject><subject>Female</subject><subject>Grip strength</subject><subject>Hand Strength</subject><subject>Health care</subject><subject>Humans</subject><subject>Muscle contraction</subject><subject>Muscle Strength</subject><subject>Muscular fatigue</subject><subject>Physical fitness</subject><subject>Quality of Life</subject><subject>Questionnaires</subject><subject>Standard deviation</subject><subject>Statistical analysis</subject><subject>Values</subject><subject>Women</subject><subject>Womens health</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkUtr3DAUhUVpaR7ttssi6KaLTCJZ1sObQjrkUZgSSlO6FLJ8PdZgSxNJbjr_PgpJQ1JtdOGc-3EPB6EPlBwz1pATt4G4HaikjaxU8wrtUyHIohaEvn4276GDlDaEMFWL5i3aY4wwQVW1j27P-h5sTjj0eDnAFPIA0Wx3-DqCyRP4jIPH3-dkR8A_cwS_zsMR_jGb0eXd_dbK9XCEz01267kMxnf41P91UFTn8e9QGPjW5QF_LcSU8dJ4C_EdetObMcH7x_8Q_To_u15eLlZXF9-Wp6uFranKi5ZYKrhsiWTAKZVGtqoI0JJW8op2tm-ZUVUNVlDetZba8jrBrVIdNKJnh-jLA3c7txN0tgSKZtTb6CYTdzoYp18q3g16Hf5oyWXDhCqAz4-AGG5mSFlPLlkYR-MhzElXdd00XHBSF-un_6ybMEdf4ulKMM6kVKIqruMHl40hpQj90zGU6PtO9ctOy8LH5xGe7P9KZHdynp-H</recordid><startdate>20201006</startdate><enddate>20201006</enddate><creator>Marques, Vitor A</creator><creator>Ferreira-Junior, João B</creator><creator>Lemos, Thiago V</creator><creator>Moraes, Rafael F</creator><creator>Junior, José Roberto de S</creator><creator>Alves, Rafael R</creator><creator>Silva, Maria S</creator><creator>Freitas-Junior, Ruffo de</creator><creator>Vieira, Carlos A</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-4145-8598</orcidid><orcidid>https://orcid.org/0000-0002-0866-6777</orcidid><orcidid>https://orcid.org/0000-0002-0083-2910</orcidid><orcidid>https://orcid.org/0000-0002-7541-8212</orcidid></search><sort><creationdate>20201006</creationdate><title>Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer</title><author>Marques, Vitor A ; 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Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (control [CNT] group, 55.8 ± 8.4 years) answered questionnaires for evaluation of fatigue (Fatigue Scale), quality of life (Short-Form Healthy Survey [SF-36] questionnaire), and anxiety (State-Trait Anxiety Inventory [IDATE]) levels. Muscle strength was also assessed by an isometric grip test and an isokinetic knee extension test. Physical limitations, social and emotional domains of quality of life were lower in the BCT group in comparison to the CNT group (
= 0.002;
= 0.003;
= 0.0003, respectively). The other domains did not differ between groups (
> 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups (
> 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group (
= 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s
(
= 0.95 and
= 0.61, respectively) and 180°.s
(
= 0.94 and
= 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33036182</pmid><doi>10.3390/ijerph17197289</doi><orcidid>https://orcid.org/0000-0003-4145-8598</orcidid><orcidid>https://orcid.org/0000-0002-0866-6777</orcidid><orcidid>https://orcid.org/0000-0002-0083-2910</orcidid><orcidid>https://orcid.org/0000-0002-7541-8212</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Anxiety Breast cancer Breast Neoplasms Cancer therapies Chemotherapy Domains Drug Therapy Evaluation Exercise Fatigue Female Grip strength Hand Strength Health care Humans Muscle contraction Muscle Strength Muscular fatigue Physical fitness Quality of Life Questionnaires Standard deviation Statistical analysis Values Women Womens health |
| title | Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer |
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