Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial

IMPORTANCE: The coronavirus disease 2019 (COVID-19) pandemic is threatening billions of people worldwide. Tocilizumab has shown promising results in retrospective studies in patients with COVID-19 pneumonia with a good safety profile. OBJECTIVE: To evaluate the effect of early tocilizumab administra...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of internal medicine (1960) 2021-01, Vol.181 (1), p.24-31
Hauptverfasser:	Salvarani, Carlo, Dolci, Giovanni, Massari, Marco, Merlo, Domenico Franco, Cavuto, Silvio, Savoldi, Luisa, Bruzzi, Paolo, Boni, Fabrizio, Braglia, Luca, Turrà, Caterina, Ballerini, Pier Ferruccio, Sciascia, Roberto, Zammarchi, Lorenzo, Para, Ombretta, Scotton, Pier Giorgio, Inojosa, Walter Omar, Ravagnani, Viviana, Salerno, Nicola Duccio, Sainaghi, Pier Paolo, Brignone, Alessandro, Codeluppi, Mauro, Teopompi, Elisabetta, Milesi, Maurizio, Bertomoro, Perla, Claudio, Norbiato, Salio, Mario, Falcone, Marco, Cenderello, Giovanni, Donghi, Lorenzo, Del Bono, Valerio, Colombelli, Paolo Luigi, Angheben, Andrea, Passaro, Angelina, Secondo, Giovanni, Pascale, Renato, Piazza, Ilaria, Facciolongo, Nicola, Costantini, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies, Monoclonal, Humanized - therapeutic use Blood Gas Analysis C-Reactive Protein - metabolism Clinical trials COVID-19 COVID-19 - drug therapy COVID-19 - metabolism COVID-19 - physiopathology Disease Progression Early Termination of Clinical Trials Female Fever Hospital Mortality Hospitalization Humans Immunosuppressive agents Intensive care Intensive Care Units - statistics & numerical data Italy Male Medical Futility Middle Aged Monoclonal antibodies Online First Original Investigation Pandemics Pneumonia Radiology Receptors, Interleukin-6 - antagonists & inhibitors Respiration, Artificial - statistics & numerical data Respiratory Insufficiency - physiopathology Respiratory Insufficiency - therapy SARS-CoV-2
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!