The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing

Understanding the mechanism that leads to immune dysfunction in severe coronavirus disease 2019 (COVID-19) is crucial for the development of effective treatment. Here, using single-cell RNA sequencing, we characterized the peripheral blood mononuclear cells (PBMCs) from uninfected controls and COVID...

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Veröffentlicht in:	Cell discovery 2020-10, Vol.6 (1), p.73-73, Article 73
Hauptverfasser:	Xu, Gang, Qi, Furong, Li, Hanjie, Yang, Qianting, Wang, Haiyan, Wang, Xin, Liu, Xiaoju, Zhao, Juanjuan, Liao, Xuejiao, Liu, Yang, Liu, Lei, Zhang, Shuye, Zhang, Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/48 631/250 Alveoli Biomedical and Life Sciences CCL4 protein CD4 antigen CD8 antigen Cell Biology Cell Culture Cell Cycle Analysis Cell death Cell Physiology Chemokines Coronaviruses COVID-19 Dendritic cells Helper cells Interferon Leukocytes (mononuclear) Life Sciences Lymphocytes Lymphocytes T Lymphopenia Macrophages Monocytes Peripheral blood mononuclear cells Ribonucleic acid RNA Stem Cells Suppressor cells T cell receptors Tumor necrosis factor
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