Comparison of chromosomal instability of human amniocytes in primary and long-term cultures in AmnioMAX II and DMEM media: A cross-sectional study

The genomic stability of stem cells to be used in cell therapy and other clinical applications is absolutely critical. In this regard, the relationship between in vitro expansion and the chromosomal instability (CIN), especially in human amniotic fluid cells (hAFCs) has not yet been completely eluci...

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Veröffentlicht in:	International Journal of Reproductive BioMedicine 2020-10, Vol.18 (10), p.885-898
Hauptverfasser:	Hoseini, Seyed Mehdi, Montazeri, Fateme, Moghaddam-Matin, Maryam, Bahrami, Ahmad Reza, Meimandi, Hassan Heidarian, Ghasemi-Esmailabad, Saeed, Kalantar, Seyed Mehdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniocentesis Chromosomes Cross-sectional studies Diagnostic tests Genetic testing human amniotic fluid cells, chromosomal instability, pseudomosaicism, amniocentesis, replicative senescence Pregnancy
Online-Zugang:	Volltext
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