Oncogenic Orphan Nuclear Receptor NR4A3 Interacts and Cooperates with MYB in Acinic Cell Carcinoma

Acinic cell carcinoma (AcCC) is a morphologically distinctive salivary gland malignancy often associated with chromosome rearrangements leading to overexpression of the NR4A3 transcription factor. However, little is known about how NR4A3 contributes to AcCC biology. Detailed RNA-sequencing of 21 arc...

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Veröffentlicht in:	Cancers 2020-08, Vol.12 (9), p.2433
Hauptverfasser:	Lee, David Y, Brayer, Kathryn J, Mitani, Yoshitsugu, Burns, Eric A, Rao, Pulivarthi H, Bell, Diana, Williams, Michelle D, Ferrarotto, Renata, Pytynia, Kristen B, El-Naggar, Adel K, Ness, Scott A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoid Artificial chromosomes Chromosome rearrangements Chromosome translocations Cloning Enhancers Gene expression Genetic transformation Genomics Health aspects Hybridization Invasiveness Lymphatic system Malignancy Proopiomelanocortin Proteins Ribonucleic acid RNA Salivary gland Salivary gland tumors Transcription factors Tumors
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