Small Molecule Inhibitors of Microenvironmental Wnt/β-Catenin Signaling Enhance the Chemosensitivity of Acute Myeloid Leukemia

Wnt/β-catenin signaling has been reported in Acute Myeloid leukemia, but little is known about its significance as a prognostic biomarker and drug target. In this study, we first evaluated the correlation between expression levels of Wnt molecules and clinical outcome. Then, we studied—in vitro and...

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Veröffentlicht in:Cancers 2020-09, Vol.12 (9), p.2696-16
Hauptverfasser: Takam Kamga, Paul, Dal Collo, Giada, Cassaro, Adriana, Bazzoni, Riccardo, Delfino, Pietro, Adamo, Annalisa, Bonato, Alice, Carbone, Carmine, Tanasi, Ilaria, Bonifacio, Massimiliano, Krampera, Mauro
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Sprache:eng
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