CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

CCAAT/enhancer-binding protein δ (C/EBPδ) is a transcription factor involved in growth arrest and differentiation, which has consequently been suggested to harbor tumor suppressive activities. However, C/EBPδ over-expression correlates with poor prognosis in glioblastoma and promotes genomic instabi...

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Veröffentlicht in:	Cancers 2020-09, Vol.12 (9), p.2546
Hauptverfasser:	Hartl, Leonie, Duitman, JanWillem, Aberson, Hella L., Chen, Kan, Dijk, Frederike, Roelofs, Joris J.T.H., Dings, Mark P.G., Hooijer, Gerrit K.J., Hernanda, Pratika Y., Pan, Qiunwei, Busch, Olivier R., Besselink, Marc G.H., Boerman, Ton, Peppelenbosch, Maikel P., Bijlsma, Maarten F., Spek, C. Arnold
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Bile Binding proteins Biopsy Breast cancer CCAAT/enhancer-binding protein Cell cycle Cell proliferation Cervical cancer Cyclin-dependent kinases Datasets DNA microarrays Gene expression Genomic instability Glioblastoma Health aspects Kinases Leukemia Lymph nodes Lymphatic system Medical prognosis Metastasis Mutation Overexpression Pancreatic cancer Physiological aspects Proteins Tumor suppressor genes Tumors
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