Network-Based Coexpression Analysis Identifies Functional and Prognostic Long Noncoding RNAs in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a primary liver cancer associated with a growing incidence and extremely high mortality. However, the pathogenic mechanism is still not fully understood. In the present study, we identified 1,631 upregulated and 1,515 downregulated genes and found that cell cycle an...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-11
Hauptverfasser:	Wang, Daijun, Wang, Can, Kai, Shuangshuang, Zhou, Jin, Li, Jianguo, Jiang, Jiying
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Biological activity Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - immunology Carcinoma, Hepatocellular - pathology Cell cycle Cell division Cell growth Cell proliferation Cell Proliferation - genetics Cytochrome Cytotoxicity Databases, Genetic Development and progression Enrichment Gene expression Gene Expression Regulation, Neoplastic Gene Ontology Gene Regulatory Networks Genetic aspects Genomes Health aspects Helper cells Hepatocellular carcinoma Hepatoma Humans Identification and classification Immune system Immunotherapy Liver cancer Liver Neoplasms - genetics Liver Neoplasms - immunology Liver Neoplasms - pathology Lymphocytes T Macrophages Medical prognosis Metabolic Networks and Pathways - genetics Metabolism Metastasis Modules Network analysis Pathogenesis Physiological aspects Prognosis Protein-protein interactions RNA RNA, Long Noncoding - genetics Signal Transduction - genetics Surveillance Survival analysis Tumor Microenvironment - genetics Tumor Microenvironment - immunology Tumor Microenvironment - physiology Tumorigenesis Tumors
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