Differential regulation of alcohol consumption and reward by the transcriptional cofactor LMO4

Repeated alcohol exposure leads to changes in gene expression that are thought to underlie the transition from moderate to excessive drinking. However, the mechanisms by which these changes are integrated into a maladaptive response that leads to alcohol dependence are not well understood. One mecha...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular psychiatry 2021-06, Vol.26 (6), p.2175-2186
Hauptverfasser:	Maiya, Rajani, Pomrenze, Matthew B., Tran, Thi, Tiwari, Gayatri R., Beckham, Andrea, Paul, Madison T., Dayne Mayfield, R., Messing, Robert O.
Format:	Artikel
Sprache:	eng
Schlagworte:	38/90 38/91 631/378 64/60 692/699/476/5 Adaptor Proteins, Signal Transducing Alcohol Alcohol Drinking - genetics Alcohol use Alcoholism Amygdala Amygdala (Brain) Animals Basolateral Nuclear Complex Behavioral Sciences Biochemistry & Molecular Biology Biological Psychology Brain Chromatin Development and progression Divergence Drinking behavior Drinking of alcoholic beverages Drug dependence Extracellular matrix Gene expression Genetic aspects Health aspects Immunoprecipitation Life Sciences & Biomedicine LIM Domain Proteins Medicine Medicine & Public Health Mice Molecular modelling Neurosciences Neurosciences & Neurology Nucleus Accumbens Opioid receptors (type kappa) Pharmacotherapy Phenotypes Physiological aspects Place preference conditioning Psychiatry Reinforcement Reward Science & Technology Transcription factors Transcription Factors - genetics Transcriptional coactivators Transcriptomes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!