Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy

The chemoresistance and toxicity of traditional chemotherapeutic drugs have become obstacles to their antitumor effects in ovarian cancers. Therefore, it is particularly important to develop new anticancer drugs to increase target sensitivity and reduce the toxicity of chemotherapy drugs. As key org...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	OncoTargets and therapy 2020, Vol.13, p.9967-9976
Hauptverfasser:	Hu, Xiaoqing, Wang, Jiabin, Chai, Jiannan, Yu, Xiaoya, Zhang, Yunhan, Feng, Yuqi, Qin, Jianchun, Yu, Huimei
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antineoplastic drugs Antitumor activity Antitumor agents Apoptosis Biotechnology industry Cancer therapies Cell viability Chemoresistance Chemotherapy Cisplatin Cytotoxicity Endoplasmic reticulum Flow cytometry Homeostasis Intracellular Membrane potential Metabolites Mitochondria Mitophagy Organelles Original Research Ovarian cancer Parkin protein Proteins PTEN-induced putative kinase Reactive oxygen species Statistical analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!