Development of novel human in vitro vascularized adipose tissue model with functional macrophages

Inflammation has been proven significant factor in development of type 2 diabetes. So far, most of the adipose tissue related research has been performed in animals, mainly rodent models. The relevance of translation of animal results to humans is questionable. However, in vitro model with relevant...

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Veröffentlicht in:	Cytotechnology (Dordrecht) 2020-10, Vol.72 (5), p.665-683
Hauptverfasser:	Huttala, Outi, Sarkanen, Jertta-Riina, Mannerström, Marika, Toimela, Tarja, Heinonen, Tuula, Ylikomi, Timo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipogenesis Adipose tissue Animal models Biochemistry Biomedicine Biotechnology Body fat Cell culture Cell growth Cell number Chemistry Chemistry and Materials Science Diabetes Diabetes mellitus (non-insulin dependent) Disease Endothelial cells Ethics Growth factors Inflammation Insulin resistance Interferon Macrophages Metabolism Monocytes Obesity Original Original Article Precision medicine Proteins Stem cells Stromal cells Umbilical cord
Online-Zugang:	Volltext
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