Catalysis of Template-Directed Nonenzymatic RNA Copying by Iron(II)

The study of nonenzymatic template-directed RNA copying is the experimental basis for the search for chemistry and reaction conditions consistent with prebiotic RNA replication. The most effective model systems for RNA copying have to date required a high concentration of Mg2+. Recently, Fe2+, which...

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Veröffentlicht in:	Journal of the American Chemical Society 2018-11, Vol.140 (44), p.15016-15021
Hauptverfasser:	Jin, Lin, Engelhart, Aaron E, Zhang, Weicheng, Adamala, Katarzyna, Szostak, Jack W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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